Johns Tanya S, Estrella Michelle M, Crews Deidra C, Appel Lawrence J, Anderson Cheryl A M, Ephraim Patti L, Cook Courtney, Boulware L Ebony
Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York;
Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland;
J Am Soc Nephrol. 2014 Nov;25(11):2649-57. doi: 10.1681/ASN.2013111207. Epub 2014 Jun 12.
Young blacks receiving dialysis have an increased risk of death compared with whites in the United States. Factors influencing this disparity among the young adult dialysis population have not been well explored. Our study examined the relation of neighborhood socioeconomic status (SES) and racial differences in mortality in United States young adults receiving dialysis. We merged US Renal Data System patient-level data from 11,027 black and white patients ages 18-30 years old initiating dialysis between 2006 and 2009 with US Census data to obtain neighborhood poverty information for each patient. We defined low SES neighborhoods as those neighborhoods in U.S. Census zip codes with ≥20% of residents living below the federal poverty level and quantified race differences in mortality risk by level of neighborhood SES. Among patients residing in low SES neighborhoods, blacks had greater mortality than whites after adjusting for baseline demographics, clinical characteristics, rurality, and access to care factors. This difference in mortality between blacks and whites was significantly attenuated in higher SES neighborhoods. In the United States, survival between young adult blacks and whites receiving dialysis differs by neighborhood SES. Additional studies are needed to identify modifiable factors contributing to the greater mortality among young adult black dialysis patients residing in low SES neighborhoods.
在美国,接受透析治疗的年轻黑人的死亡风险高于白人。影响年轻成人透析人群中这种差异的因素尚未得到充分探究。我们的研究考察了美国接受透析治疗的年轻成人中社区社会经济地位(SES)与死亡率种族差异之间的关系。我们将2006年至2009年间开始透析治疗的11027名18至30岁黑人和白人患者的美国肾脏数据系统患者层面数据与美国人口普查数据合并,以获取每位患者的社区贫困信息。我们将低SES社区定义为美国人口普查邮政编码区域中居民生活在联邦贫困线以下比例≥20%的社区,并按社区SES水平对死亡率风险的种族差异进行量化。在居住在低SES社区的患者中,在调整基线人口统计学、临床特征、农村地区以及医疗服务可及性因素后,黑人的死亡率高于白人。在较高SES社区中,黑人和白人之间的这种死亡率差异显著减弱。在美国,接受透析治疗的年轻成人黑人和白人之间的生存率因社区SES而异。需要进一步研究以确定导致居住在低SES社区的年轻成人黑人透析患者死亡率更高的可改变因素。