Cardigno P
Homeopathic Clinical Research, Scientific Department FIAMO-Homeosynesis Medical Association, Colorno, Italy.
Homeopathy. 2009 Apr;98(2):97-106. doi: 10.1016/j.homp.2009.01.004.
A preliminary study to evaluate the usefulness of homeopathic treatment in the care of menstrual irregularities.
Patients were diagnosed at the first appointment according to menstrual cycle over the past year: Amenorrhea (AM), Oligo-amenorrhea (OL-AM), OL, Taking hormone replacement therapy (HRT). All patients were prescribed an individualised, global homeopathic treatment. The main outcomes were: time to resumption of periods, change of clinical diagnosis at the end of follow-up or after 2 years. The secondary outcomes were: menstrual regularity at the end of follow-up, compared to pre-treatment frequency; flow characteristics; clinical course of acute and chronic concomitant symptoms.
18 consecutive cases of secondary amenorrhea (SA) and oligomenorrhea (OL) met the entry criteria. 8 women had SA, 2 were on HRT, 6 had OL-AM and 2 had OL. The average duration of considered follow-up was 21 months. The average time before the reappearance of menstruation was 58 days (s.d. 20) in the 8 women with SA at the time of the first appointment, for all cases 46 days (s.d. 42). Change of clinical diagnosis: 50% of women, who were diagnosed AM, recovered their ovulatory cycle (OV), whereas 12.5% remained amenorrheic; 33.3% of patients, who were initially OL-AM, showed an OV; 100% of oligomenorrheic and HRT patients recovered an OV. The average frequency of spontaneous cycles per year changes from 4.32 (s.d. 1.97) pre-treatment to 9.6 cycles per year at the end (s.d. 2.92). Four detailed case histories are reported.
一项初步研究，以评估顺势疗法在月经不调护理中的效用。
根据过去一年的月经周期，在首次就诊时对患者进行诊断：闭经（AM）、月经过少性闭经（OL-AM）、月经稀发（OL）、接受激素替代疗法（HRT）。所有患者均接受个体化的整体顺势疗法治疗。主要结局指标为：月经恢复时间、随访结束时或2年后临床诊断的变化。次要结局指标为：随访结束时与治疗前频率相比的月经规律性；经量特征；急慢性伴随症状的临床病程。
18例继发性闭经（SA）和月经稀发（OL）连续病例符合纳入标准。8名女性患有SA，2名正在接受HRT，6名患有OL-AM，2名患有OL。考虑的平均随访时间为21个月。首次就诊时8名SA女性月经再次出现的平均时间为58天（标准差20），所有病例为46天（标准差42）。临床诊断变化：诊断为AM的女性中，50%恢复了排卵周期（OV），而12.5%仍为闭经；最初为OL-AM的患者中，33.3%出现了OV；所有月经稀发和HRT患者均恢复了OV。每年自发周期的平均频率从治疗前的4.32（标准差1.97）变为随访结束时的每年9.6个周期（标准差2.92）。报告了4例详细的病例史。
