Rollag A, Abdelnoor M, Mangschau A, Jonsbu J, Aase O, Erikssen J
Department of Internal Medicine, Central Hospital of Akershus, Nordbyhagen, Norway.
Eur Heart J. 1991 Sep;12(9):968-73.
Five-year survival amongst 485 consecutive patients with their first acute myocardial infarction (AMI) was 78.2%. Univariate survival analysis showed that the following variables during the acute stage were of prognostic significance for survival: signs of left ventricular heart failure, enlarged cardiac volume, pulmonary congestion on chest X-ray, anterior myocardial infarction on ECG, and low left ventricular ejection fraction (LVEF), whereas enzyme analysis and Q/non-Q signs on ECG were not. In the multivariate analysis two equivalent models were found. The first pinpointed age and LVEF as independent predictors of mortality, and the second age and left ventricular heart failure. Finally, our subcohort of patients aged less than the mean 63 years and with normal LVEF values of greater than or equal to 50%, or no left ventricular failure had an observed survival for 5 years close to an age- and sex-matched group from the Norwegian population.
485例首次发生急性心肌梗死（AMI）的连续患者的5年生存率为78.2%。单因素生存分析表明，急性期的以下变量对生存具有预后意义：左心室心力衰竭体征、心腔扩大、胸部X线显示肺充血、心电图显示前壁心肌梗死以及低左心室射血分数（LVEF），而酶分析和心电图上的Q波/非Q波征象则无预后意义。多因素分析发现了两个等效模型。第一个模型确定年龄和LVEF为死亡率的独立预测因素，第二个模型确定年龄和左心室心力衰竭为死亡率的独立预测因素。最后，我们的亚组患者年龄小于平均63岁，LVEF值正常且大于或等于50%，或无左心室衰竭，其5年观察生存率接近来自挪威人群的年龄和性别匹配组。
