Université Paris Descartes; Hôpital Necker Enfants Malades, Service de Pneumologie et d'Allergologie Pédiatriques, 149 rue de Sèvres, Paris, France.
Respir Med. 2009 Sep;103(9):1383-91. doi: 10.1016/j.rmed.2009.03.006. Epub 2009 Apr 9.
The goal of asthma management focuses on adequate control of asthma, although little is known about the optimal level of asthma control to be reached. The ELIOS study was conducted in France to address this lack of information.
Cross-sectional study of asthmatic children (4-15 years) visiting their medical practitioner. The primary objective was to assess the level of asthma control with a 3-level composite score based on French (ANAES) guidelines criteria (optimal, acceptable, and unacceptable).
Asthma control was assessed in 3431 children and classified as optimal (26%), acceptable (41.3%), and unacceptable (32.7%). When PEFR was studied, asthma control was optimal in 23.0%, acceptable in 35.8% and unacceptable in 41.2% (p<0.001) of children. Unacceptable asthma control was significantly associated with higher BMI (p=0.002), more recent diagnosis of asthma (p=0.008), passive exposure to parental tobacco smoke (p<0.001), number of associated allergic diseases (p<0.001), frequent respiratory tract infections (p<0.001) and low socioeconomic status (p<0.001). Multivariate analysis identified presence of respiratory tract infections (p<0.0001), passive exposure to parental tobacco smoke (p=0.009) and low socioeconomic status (p=0.042) as variables associated with unacceptable asthma control.
There is room for improvement in France as only 25% of asthmatic children are optimally controlled. Public health strategies should increase awareness among physicians and parents about the importance of using asthma control tools, eliminating exposure to tobacco smoke and treating associated allergic diseases.
哮喘管理的目标是实现哮喘的充分控制,但对于达到何种哮喘控制水平最佳尚缺乏了解。ELIOS 研究在法国开展,旨在解决这一信息空白。
这是一项针对就诊于医生的哮喘儿童(4-15 岁)的横断面研究。主要目的是根据法国(ANAES)指南标准(最佳、可接受和不可接受),使用三级综合评分评估哮喘控制水平。
共评估了 3431 名儿童的哮喘控制情况,分为控制良好(26%)、可接受(41.3%)和控制不佳(32.7%)。当评估 PEFR 时,哮喘控制良好的儿童占 23.0%,可接受的占 35.8%,控制不佳的占 41.2%(p<0.001)。不可接受的哮喘控制与更高的 BMI(p=0.002)、哮喘近期诊断(p=0.008)、父母被动吸烟(p<0.001)、合并的过敏性疾病数量(p<0.001)、频繁的呼吸道感染(p<0.001)和低社会经济地位(p<0.001)显著相关。多变量分析确定了呼吸道感染(p<0.0001)、父母被动吸烟(p=0.009)和低社会经济地位(p=0.042)是与不可接受的哮喘控制相关的变量。
法国有改善的空间,只有 25%的哮喘儿童得到了充分控制。公共卫生策略应提高医生和家长对使用哮喘控制工具、消除吸烟暴露和治疗合并的过敏性疾病的重要性的认识。