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Recovery of diverse genes for class 1 integron-integrases from environmental DNA samples.从环境DNA样本中回收1类整合子整合酶的多种基因。
FEMS Microbiol Lett. 2008 Oct;287(1):56-62. doi: 10.1111/j.1574-6968.2008.01291.x. Epub 2008 Aug 1.
2
Influence of industrial contamination on mobile genetic elements: class 1 integron abundance and gene cassette structure in aquatic bacterial communities.工业污染对移动遗传元件的影响：水生细菌群落中1类整合子丰度及基因盒结构
ISME J. 2008 Apr;2(4):417-28. doi: 10.1038/ismej.2008.8. Epub 2008 Feb 14.
3
Integron-associated gene cassettes in Halifax Harbour: assessment of a mobile gene pool in marine sediments.哈利法克斯港中与整合子相关的基因盒：海洋沉积物中一个可移动基因库的评估
Environ Microbiol. 2008 Apr;10(4):1024-38. doi: 10.1111/j.1462-2920.2007.01524.x. Epub 2008 Jan 7.
4
Identification of key structural determinants of the IntI1 integron integrase that influence attC x attI1 recombination efficiency.鉴定影响attC与attI1重组效率的IntI1整合子整合酶的关键结构决定因素。
Nucleic Acids Res. 2007;35(19):6475-89. doi: 10.1093/nar/gkm709. Epub 2007 Sep 20.
5
Novel and diverse integron integrase genes and integron-like gene cassettes are prevalent in deep-sea hydrothermal vents.新型且多样的整合子整合酶基因及类整合子基因盒在深海热液喷口中普遍存在。
Environ Microbiol. 2007 Sep;9(9):2298-312. doi: 10.1111/j.1462-2920.2007.01344.x.
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Integrons: mobilizable platforms that promote genetic diversity in bacteria.整合子：促进细菌遗传多样性的可移动平台。
Trends Microbiol. 2007 Jul;15(7):301-9. doi: 10.1016/j.tim.2007.05.004. Epub 2007 Jun 12.
7
Molecular differentiation of common promoters in Salmonella class 1 integrons.沙门氏菌1类整合子中常见启动子的分子分化
J Microbiol Methods. 2007 Mar;68(3):453-7. doi: 10.1016/j.mimet.2006.09.019. Epub 2006 Nov 22.
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Structural basis for broad DNA-specificity in integron recombination.整合子重组中广泛DNA特异性的结构基础。
Nature. 2006 Apr 27;440(7088):1157-62. doi: 10.1038/nature04643.
9
Integrons in Xanthomonas: a source of species genome diversity.黄单胞菌中的整合子：物种基因组多样性的一个来源
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The ProDom database of protein domain families: more emphasis on 3D.蛋白质结构域家族的ProDom数据库：更注重三维结构。
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整合子的首个基因盒作为在宏基因组中寻找适应性基因的靶点。

First gene cassettes of integrons as targets in finding adaptive genes in metagenomes.

作者信息

Huang Lionel, Cagnon Christine, Caumette Pierre, Duran Robert

机构信息

Université de Pau et des Pays de l'Adour, IPREM UMR CNRS, IBEAS, BP, Pau, France.

出版信息

Appl Environ Microbiol. 2009 Jun;75(11):3823-5. doi: 10.1128/AEM.02394-08. Epub 2009 Apr 10.

DOI:10.1128/AEM.02394-08
PMID:19363073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2687265/
Abstract

The first gene cassettes of integrons are involved in the last adaptation response to changing conditions and are also the most expressed. We propose a rapid method for the selection of clones carrying an integron first gene cassette that is useful for finding adaptive genes in environmental metagenomic libraries.

摘要

整合子的首个基因盒参与了对不断变化条件的最终适应性反应，且也是表达量最高的。我们提出了一种快速方法，用于筛选携带整合子首个基因盒的克隆，该方法有助于在环境宏基因组文库中寻找适应性基因。