Arbak Peri, Balbay Oner, Annakkaya Ali Nihat, Bilgin Cahit, Ozsahin Sefa Levent
Faculty of Medicine, Department of Chest Diseases, Duzce University, 81620 Konuralp, Duzce, Turkey.
Ind Health. 2009 Apr;47(2):160-5. doi: 10.2486/indhealth.47.160.
Diesel exhaust (DE) has been accused for various health outcomes including exacerbation of asthma, chronic bronchitis. Exposure to DE has long-term effects on lung development in children and reductions in lung function have been reported. The aim of the study was to evaluate the annual changes in forced expiratory flows among toll collectors in Duzce city from 2002 to 2005. Annual FVC, FEV(1) and MMF changes in smoker and nonsmoker 58 toll collectors and 37 controls selected among men who worked in the same company as officer have been followed up. No significant changes were seen in expiratory flows among smoker-nonsmoker toll collectors and controls (p>0.05). Annual FVC, FEV(1) and MMF changes were not significantly different between smoker and nonsmoker toll collectors. Twelve toll collectors (20.7%) in the study group and 4 (10.8%) controls were found to have FEV(1) and FVC below longitudinal lower limit of normal. The difference between groups did not reach statistically significance (p>0.05). Toll collectors (18/58) and controls (15/37) with spirometric measurements for three times showed no difference according to the rate of annual difference in either FEV(1) (-21.3+/-133.1 ml/yr vs -44.3+/-166.6 (ml/yr) or FVC (13.2+/-202.9 ml/yr vs. -16.1+/-204.2 ml/yr). Further investigations including large groups with long term follow up are needed to observe annual FVC, FEV(1) and MMF changes among toll collectors.
柴油废气（DE）被认为会导致多种健康问题，包括哮喘加重、慢性支气管炎。接触DE对儿童肺部发育有长期影响，且已有报告称其会降低肺功能。本研究的目的是评估2002年至2005年期间杜兹市收费站工作人员的用力呼气流量的年度变化。对58名收费站工作人员（吸烟者和非吸烟者）以及37名对照人员（从与收费站工作人员在同一家公司工作的男性中选取）的年度用力肺活量（FVC）、第一秒用力呼气容积（FEV₁）和最大呼气中期流速（MMF）变化进行了跟踪。在吸烟者和非吸烟者收费站工作人员及对照人员中，呼气流量均未出现显著变化（p>0.05）。吸烟者和非吸烟者收费站工作人员的年度FVC、FEV₁和MMF变化无显著差异。研究组中有12名收费站工作人员（20.7%）和4名对照人员（10.8%）的FEV₁和FVC低于正常纵向下限。两组之间的差异未达到统计学显著性（p>0.05）。进行了三次肺功能测量的收费站工作人员（18/58）和对照人员（15/37），其FEV₁（-21.3±133.1 ml/年 vs -44.3±166.6（ml/年））或FVC（13.2±202.9 ml/年 vs. -16.1±204.2 ml/年）的年度差异率无差异。需要进一步开展包括大样本长期随访的研究，以观察收费站工作人员的年度FVC、FEV₁和MMF变化。
