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扇叶蒲葵和棕榈果浆亲脂性部分的化学特征分析及其降血脂和抗溃疡活性评估(棕榈科)

Chemical characterization of the lipophilic fraction of Livistona decipiens and Livistona chinensis fruit pulps (Palmae) and assessment of their anti-hyperlipidemic and anti-ulcer activities.

作者信息

Kadry Hazem, Shoala Soha, El Gindi Omayma, Sleem Amany A, Mosharrafa Salwa, Kassem Mona

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Nasr City 1137, Al Azhar University, Cairo, Egypt.

出版信息

Nat Prod Commun. 2009 Feb;4(2):265-70.

Abstract

The oil of the dried pulps of Livistona decipiens and L. chinensis palm fruits have been studied for the first time by gas chromatography-mass spectrometry for their unsaponifiable matter (USM) and fatty acid composition (FAME). The antihyperlipidemic and anti-ulcer activities for both oils were also assayed. The principal fatty acid of L. decipiens pulp oil was oleic acid (53.4 %) and of L. chinensis pulp oil palmitic acid (47.4 %). In relation to anti-hyperlipidemic properties, the pulp oil of L. decipiens presented a better profile than that of L. chinensis, in comparison with the reference standard (simvastatin). In addition, both pulp oils showed high anti-ulcer activity using an indomethacin-induced ulceration technique in rat stomach. The relationship between the anti-hyperlipidemic, anti-ulcer and chemical composition of the pulp oils is also discussed.

摘要

首次采用气相色谱 - 质谱联用技术对扇叶葵和棕榈的干燥果肉油中的不皂化物(USM)和脂肪酸组成(FAME)进行了研究。同时测定了这两种油的抗高血脂和抗溃疡活性。扇叶葵果肉油的主要脂肪酸是油酸(53.4%),而棕榈果肉油的主要脂肪酸是棕榈酸(47.4%)。在抗高血脂特性方面,与参考标准品(辛伐他汀)相比,扇叶葵的果肉油表现出比棕榈更好的特性。此外,在大鼠胃中采用吲哚美辛诱导溃疡技术时,两种果肉油均显示出较高的抗溃疡活性。还讨论了果肉油的抗高血脂、抗溃疡与化学成分之间的关系。

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