西葫芦成熟果实果肉提取物对阿司匹林诱导的大鼠胃溃疡和十二指肠溃疡的影响。
Effect of ripe fruit pulp extract of Cucurbita pepo Linn. in aspirin induced gastric and duodenal ulcer in rats.
作者信息
Sarkar Sentu, Buha Debjani
机构信息
S.N. Pradhan Centre for Neurosciences, University of Calcutta 244B, A.J.C. Bose Road, Kolkata 700 020, India.
出版信息
Indian J Exp Biol. 2008 Sep;46(9):639-45.
PMID:18949893
Abstract
A significant decrease in alkaline phosphatase (AP) activity and mucosal thickness and increase in ulcer index (UI) was observed in aspirin treated stomach and duodenum of albino rats. However, pretreatment with C. pepo fruit pulp extract for 14 consecutive days showed increase in AP activity and mucosal thickness along with decrease in UI, suggesting gastroduodenal protective and anti-ulcerogenic properties of C. pepo.
摘要
在白化大鼠经阿司匹林处理的胃和十二指肠中，观察到碱性磷酸酶（AP）活性和黏膜厚度显著降低，溃疡指数（UI）升高。然而，连续14天用西葫芦果肉提取物预处理显示AP活性和黏膜厚度增加，同时UI降低，这表明西葫芦具有胃十二指肠保护和抗溃疡特性。
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