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[经自然腔道内镜手术(NOTES):初步实验结果]

[Natural orifice transluminal endoscopic surgery (NOTES): initial experimental results].

作者信息

Olsina Kissler Jorge Juan, Balsells Valls Joaquín, Dot Bach Juan, Suboh Abadia Monder Abu, Armengol Bertroli Jordi, Esteves Marielle, Rosal Fontana Marta, Armengol-Miró José Ramón

机构信息

World Institute for Digestive Endoscopy Research, WIDER-Barcelona (colaboración Obra Social Fundación La Caixa), Barcelona, España.

出版信息

Cir Esp. 2009 May;85(5):298-306. doi: 10.1016/j.ciresp.2008.11.007. Epub 2009 Apr 18.

DOI:10.1016/j.ciresp.2008.11.007
PMID:19376503
Abstract

INTRODUCTION

The advent of natural orifice endoscopic surgery (NOTES) and new prototypes for performing this surgical procedure led us to design an experimental animal surgical programme.

MATERIAL AND METHOD

NOTES was performed over a period of one year, in sows, following the European guidelines on the use of experimental animals. Ninety operations were performed with no animals surviving. The following aspects were assessed: 1. Access route complexity (transgastric, transvaginal, transesophageal and transumbilical). 2. Support measures for temporal/spatial orientation. 3. Technical possibilities for visceral orifice closure (clips, T-bars, Obesco clips and endoscopic suture). Resections of fallopian tubes, ovaries, gallbladder, mediastinal lymph nodes, tail of the pancreas and gastrojejunal derivations were performed with one or two endoscopes.

RESULTS

This experience enabled us to highlight a series of technical aspects essential for these techniques: 1. Pneumoperitoneum with CO(2) is safer for entry. 2. Orifice size is important to limit contamination. 3. Puncture entry and guided dilation is safer. 4. Good gastric exit location makes it easier to approach viscera to be resected. 5. Intra-abdominal haemorrhage is difficult to control. 6. Leak-free closure cannot be guaranteed with clips, but t-bars and Obesco clips may be effective. 7. Endoscopes that permit triangulation may facilitate the dissection and endoscopic suture.

CONCLUSIONS

NOTES requires a multidisciplinary team comprising laparoscopic and endoscopic surgeons. Pure NOTES is complex and hybrid forms or transumbilical route could be intermediate steps.

摘要

引言

自然腔道内镜手术(NOTES)的出现以及用于实施该手术的新原型促使我们设计了一项实验动物外科手术方案。

材料与方法

按照欧洲关于实验动物使用的指南,在母猪身上进行了为期一年的NOTES手术。共进行了90例手术,无动物存活。评估了以下几个方面:1. 进入途径的复杂性(经胃、经阴道、经食管和经脐)。2. 时间/空间定位的支持措施。3. 内脏孔闭合的技术可能性(夹子、T形夹、Obesco夹和内镜缝合)。使用一或两个内镜进行输卵管、卵巢、胆囊、纵隔淋巴结、胰尾和胃空肠改道术的切除。

结果

该经验使我们能够突出这些技术所必需的一系列技术要点:1. 使用CO₂建立气腹用于进入更安全。2. 孔的大小对于限制污染很重要。3. 穿刺进入和引导扩张更安全。4. 良好的胃出口位置便于接近要切除的内脏。5. 腹腔内出血难以控制。6. 夹子不能保证无渗漏闭合,但T形夹和Obesco夹可能有效。7. 允许三角定位的内镜可能有助于解剖和内镜缝合。

结论

NOTES需要一个由腹腔镜和内镜外科医生组成的多学科团队。单纯的NOTES很复杂,混合形式或经脐途径可能是中间步骤。

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1
[Natural orifice transluminal endoscopic surgery (NOTES): initial experimental results].[经自然腔道内镜手术(NOTES):初步实验结果]
Cir Esp. 2009 May;85(5):298-306. doi: 10.1016/j.ciresp.2008.11.007. Epub 2009 Apr 18.
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Dual-port distal pancreatectomy using a prototype endoscope and endoscopic stapler: a natural orifice transluminal endoscopic surgery (NOTES) survival study in a porcine model.使用原型内窥镜和内镜吻合器的双端口远端胰腺切除术:猪模型中的经自然腔道内镜手术(NOTES)生存研究
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Natural orifice transluminal endoscopic surgery (NOTES) in the mediastinum: long-term survival animal experiments in transesophageal access, including minor surgical procedures.纵隔自然腔道内镜手术(NOTES):经食管入路的长期生存动物实验,包括小型外科手术。
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Evaluation for transvaginal and transgastric NOTES cholecystectomy in human and animal natural orifice translumenal endoscopic surgery.经阴道和经胃自然腔道内镜手术(NOTES)行胆囊切除术在人和动物中的评估。
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