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Infect Immun. 1977 May;16(2):717-9. doi: 10.1128/iai.16.2.717-719.1977.
2
Acute and latent herpes simplex virus neurological disease in mice immunized with purified virus-specific glycoproteins gB or gD.用纯化的病毒特异性糖蛋白gB或gD免疫的小鼠中的急性和潜伏性单纯疱疹病毒神经疾病
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Immunization with a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: long-term protection and effect of revaccination.用表达单纯疱疹病毒1型糖蛋白D的痘苗病毒重组体进行免疫接种：长期保护及再次接种的效果。
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Helper T cells induced by an immunopurified herpes simplex virus type I (HSV-I) 115 kilodalton glycoprotein (gB) protect mice against HSV-I infection.由免疫纯化的单纯疱疹病毒I型（HSV-I）115千道尔顿糖蛋白（gB）诱导的辅助性T细胞可保护小鼠免受HSV-I感染。
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Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection.用1型单纯疱疹病毒复制缺陷型突变体进行免疫接种：在攻击病毒感染发病机制中的免疫干预位点。
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Experimental ulcerative herpetic keratitis. IV. Preliminary observations on the efficacy of a herpes simplex subunit vaccine.实验性溃疡性疱疹性角膜炎。IV. 单纯疱疹亚单位疫苗疗效的初步观察
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The influence of different modes of immunization on the experimental genital herpes simplex virus infection of mice.不同免疫方式对小鼠实验性生殖器单纯疱疹病毒感染的影响。
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Immune responses in mice against herpes simplex virus: mechanisms of protection against facial and ganglionic infections.小鼠针对单纯疱疹病毒的免疫反应：预防面部和神经节感染的机制
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本文引用的文献

1
The Axis-Cylinders of Peripheral Nerves as Portals of Entry to the Central Nervous System for the Virus of Herpes Simplex in Experimentally Infected Rabbits.在实验感染的兔子中，外周神经的轴突圆柱体作为单纯疱疹病毒进入中枢神经系统的门户。
Am J Pathol. 1925 Jan;1(1):11-28.5.
2
THE PATHOGENESIS OF HERPES VIRUS ENCEPHALITIS. II. A CELLULAR BASIS FOR THE DEVELOPMENT OF RESISTANCE WITH AGE.疱疹病毒性脑炎的发病机制。II. 随年龄增长产生抵抗力的细胞基础。
J Exp Med. 1964 Sep 1;120(3):359-74. doi: 10.1084/jem.120.3.359.
3
THE PATHOGENESIS OF HERPES VIRUS ENCEPHALITIS. I. VIRUS PATHWAYS TO THE NERVOUS SYSTEM OF SUCKLING MICE DEMONSTRATED BY FLUORESCENT ANTIBODY STAINING.疱疹病毒性脑炎的发病机制。I. 用荧光抗体染色法显示乳鼠神经系统的病毒传播途径。
J Exp Med. 1964 Feb 1;119(2):343-56. doi: 10.1084/jem.119.2.343.
4
Depression of acquired resistance against herpes simplex virus infection in neonatally thymectomized mice.
Arch Gesamte Virusforsch. 1967;21(3):459-62. doi: 10.1007/BF01241745.
5
Herpes virus latency in spinal ganglia of mice without illness.疱疹病毒在未患病小鼠脊髓神经节中的潜伏状态。
Proc Soc Exp Biol Med. 1974 Sep;146(4):1093-6. doi: 10.3181/00379727-146-38251.
6
Infection with herpes-simplex viruses 1 and 2. 3.单纯疱疹病毒1型和2型感染。3.
N Engl J Med. 1973 Oct 11;289(15):781-9. doi: 10.1056/NEJM197310112891505.
7
Infection with herpes-simplex viruses 1 and 2. II.单纯疱疹病毒1型和2型感染。II.
N Engl J Med. 1973 Oct 4;289(14):719-25. doi: 10.1056/NEJM197310042891404.
8
A review of the identification and titration of antibodies to herpes simplex viruses type 1 and type 2 in human sera.人血清中1型和2型单纯疱疹病毒抗体的鉴定与滴定综述。
Cancer Res. 1973 Jun;33(6):1469-76.
9
Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection.小鼠疱疹性神经炎和神经节炎的发病机制：感染轴突内运输的证据
Infect Immun. 1973 Feb;7(2):272-88. doi: 10.1128/iai.7.2.272-288.1973.
10
Type 1 and type 2 herpes simplex viruses: serological and biological differences.1型和2型单纯疱疹病毒：血清学和生物学差异
J Virol. 1970 Jan;5(1):51-9. doi: 10.1128/JVI.5.1.51-59.1970.

1型单纯疱疹病毒免疫对小鼠抵御2型单纯疱疹病毒急性和潜伏感染的效果。

Efficacy of herpes simplex virus type 1 immunization in protecting against acute and latent infection by herpes simplex virus type 2 in mice.

作者信息

McKendall R R

出版信息

Infect Immun. 1977 May;16(2):717-9. doi: 10.1128/iai.16.2.717-719.1977.

DOI:10.1128/iai.16.2.717-719.1977
PMID:193798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421016/
Abstract

ICR mice were immunized with herpes simplex virus type 1 (HSV-1) and later challenged with HSV-2 by footpad inoculation. Both immunized animals and age-matched, nonimmunized controls were observed for ascending neurological disease and latent infection of spinal ganglia resulting from the HSV-2 challenge. Control animals had a 78% incidence of acute and latent infection compared with a 1.7% incidence in immunized mice. The data show immunity to HSV-1 is protective against both acute and latent infection by HSV-2.

摘要

将1型单纯疱疹病毒（HSV-1）免疫ICR小鼠，随后通过足垫接种用HSV-2攻击。观察免疫动物和年龄匹配的未免疫对照，以了解由HSV-2攻击导致的上行性神经疾病和脊髓神经节的潜伏感染情况。对照动物急性和潜伏感染的发生率为78%，而免疫小鼠的发生率为1.7%。数据表明，对HSV-1的免疫可预防HSV-2的急性和潜伏感染。