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实验性溃疡性疱疹性角膜炎。IV. 单纯疱疹亚单位疫苗疗效的初步观察

Experimental ulcerative herpetic keratitis. IV. Preliminary observations on the efficacy of a herpes simplex subunit vaccine.

作者信息

Carter C A, Hartley C E, Skinner G R, Turner S P, Easty D L

出版信息

Br J Ophthalmol. 1981 Oct;65(10):679-82. doi: 10.1136/bjo.65.10.679.

DOI:10.1136/bjo.65.10.679
PMID:6274376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1039636/
Abstract

Systemic vaccination of rabbits with an inactivated type 1 virus subunit vaccine induced humoral and cell-mediated immune responses. Following ocular infection with type 1 herpes virus corneal ulceration and virus excretion were reduced in the vaccinated rabbits.

摘要

用灭活的1型病毒亚单位疫苗对兔进行全身接种可诱导体液免疫和细胞介导的免疫反应。在用1型疱疹病毒进行眼部感染后，接种疫苗的兔角膜溃疡和病毒排泄减少。

相似文献

1
Experimental ulcerative herpetic keratitis. IV. Preliminary observations on the efficacy of a herpes simplex subunit vaccine.实验性溃疡性疱疹性角膜炎。IV. 单纯疱疹亚单位疫苗疗效的初步观察
Br J Ophthalmol. 1981 Oct;65(10):679-82. doi: 10.1136/bjo.65.10.679.
2
Protection from experimental ocular herpetic keratitis by a heat-killed virus vaccine.热灭活病毒疫苗对实验性眼部疱疹性角膜炎的保护作用。
Arch Ophthalmol. 1980 May;98(5):893-6. doi: 10.1001/archopht.1980.01020030887017.
3
Investigation of a sub-unit vaccine using an animal model of herpes simplex keratitis.使用单纯疱疹性角膜炎动物模型对亚单位疫苗进行研究。
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 3):342-6.
4
Experimental ulcerative herpetic keratitis. I. Systemic immune responses and resistance to corneal infection.实验性溃疡性疱疹性角膜炎。I. 全身免疫反应及对角膜感染的抵抗力
Br J Ophthalmol. 1981 Feb;65(2):77-81. doi: 10.1136/bjo.65.2.77.
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A therapeutic vaccine that reduces recurrent herpes simplex virus type 1 corneal disease.一种可减少复发性单纯疱疹病毒1型角膜疾病的治疗性疫苗。
Invest Ophthalmol Vis Sci. 1998 Jun;39(7):1163-70.
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[Dynamics of cellular immunity indices in patients with ophthalmic herpes treated with a herpetic polyvaccine].[用疱疹多价疫苗治疗的眼部疱疹患者细胞免疫指标的动态变化]
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Ocular safety and efficacy of an HSV-1 gD vaccine during primary and latent infection.单纯疱疹病毒1型糖蛋白D疫苗在原发感染和潜伏感染期间的眼部安全性和有效性。
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[Short-term therapeutic effect of an inactivated herpes simplex virus type 1 vaccine on herpes simplex keratitis].1型单纯疱疹病毒灭活疫苗对单纯疱疹性角膜炎的短期治疗效果
Zhonghua Yan Ke Za Zhi. 1983 Nov;19(6):339-42.
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[Anti-herpetic vaccination by nasal route in rabbits].[兔经鼻途径抗疱疹病毒疫苗接种]
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Herpetic stromal keratitis-evidence for cell-mediated immunopathogenesis.疱疹性基质性角膜炎——细胞介导免疫发病机制的证据
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引用本文的文献

1
Immunogenicity and protective efficacy in a rhesus monkey model of vaccine Ac NFUi(S-) MRC against primary type 2 herpes simplex virus infection.疫苗Ac NFUi(S-) MRC针对恒河猴原发性2型单纯疱疹病毒感染的免疫原性和保护效果
Br J Exp Pathol. 1982 Aug;63(4):378-87.
2
Preparation and immunogenicity of vaccine Ac NFU1 (S-) MRC towards the prevention of herpes genitalis.用于预防生殖器疱疹的疫苗Ac NFU1 (S-) MRC的制备及免疫原性
Br J Vener Dis. 1982 Dec;58(6):381-6. doi: 10.1136/sti.58.6.381.
3
Follow-up report on 50 subjects vaccinated against herpes genitalis with Skinner vaccine.关于50名接种斯金纳疫苗预防生殖器疱疹受试者的随访报告。
Med Microbiol Immunol. 1987;176(3):161-8. doi: 10.1007/BF00193897.
4
Report of twelve years experience in open study of Skinner herpes simplex vaccine towards prevention of herpes genitalis.斯金纳单纯疱疹疫苗预防生殖器疱疹开放研究十二年经验报告。
Med Microbiol Immunol. 1992;180(6):305-20. doi: 10.1007/BF00191551.

本文引用的文献

1
A sensitive and precise plaque assay for herpes virus.一种用于疱疹病毒的灵敏且精确的蚀斑测定法。
Nature. 1962 Sep 8;195:1028-9. doi: 10.1038/1951028a0.
2
Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.仓鼠细胞克隆的多瘤病毒转化——对影响细胞感受态的遗传因素的研究
Virology. 1962 Feb;16:147-51. doi: 10.1016/0042-6822(62)90290-8.
3
THERAPEUTIC CONSIDERATIONS IN OCULAR VACCINIA.眼部牛痘的治疗考量
Trans Ophthalmol Soc U K (1962). 1963;83:613-31.
4
Immunization of mice with inactivated herpes simplex virus.用灭活的单纯疱疹病毒对小鼠进行免疫接种。
Proc Soc Exp Biol Med. 1961 Jul;107:518-20. doi: 10.3181/00379727-107-26673.
5
Experimental ulcerative herpetic keratitis. I. Systemic immune responses and resistance to corneal infection.实验性溃疡性疱疹性角膜炎。I. 全身免疫反应及对角膜感染的抵抗力
Br J Ophthalmol. 1981 Feb;65(2):77-81. doi: 10.1136/bjo.65.2.77.
6
Prepubertal vaccination of mice against experimental infection of the genital tract with type 2 herpes simplex virus.对小鼠进行青春期前接种疫苗，以预防2型单纯疱疹病毒对生殖道的实验性感染。
Arch Virol. 1980;64(4):329-38. doi: 10.1007/BF01320618.
7
Protection from experimental ocular herpetic keratitis by a heat-killed virus vaccine.热灭活病毒疫苗对实验性眼部疱疹性角膜炎的保护作用。
Arch Ophthalmol. 1980 May;98(5):893-6. doi: 10.1001/archopht.1980.01020030887017.
8
Precipitating antibodies to herpes simplex virus in human sera: prevalence of antibody to common antigen (band II).人血清中单纯疱疹病毒沉淀抗体：常见抗原（II带）抗体的流行情况
Intervirology. 1974;4(5):320-4. doi: 10.1159/000149865.
9
Differentiation between type 1 and type 2 strains of herpes simplex virus by an indirect immunofluorescent technique.用间接免疫荧光技术区分单纯疱疹病毒1型和2型毒株。
J Gen Virol. 1971 Aug;12(2):179-82. doi: 10.1099/0022-1317-12-2-179.
10
Topical vaccine therapy in herpetic keratitis.疱疹性角膜炎的局部疫苗疗法。
Lancet. 1970 May 16;1(7655):1064. doi: 10.1016/s0140-6736(70)91202-x.