Wosnitza M, Bozkurt A, O'Dey D, Pallua N, Megahed M
Klinik für Allergologie und Dermatologie, Universitätsklinikum RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Deutschland.
Hautarzt. 2009 May;60(5):366-8. doi: 10.1007/s00105-009-1748-7.
A 67-year old patient developed multiple flesh-colored nodules on the back of his left hand. Histological examination led to the diagnosis of a Merkel cell carcinoma (MCC). This highly aggressive primary cutaneous tumor is classified as a neuroendocrine carcinoma. It affects mostly elderly and immunosuppressed patients. Recently, a new polyomavirus (MCPyV) has been detected in about 75-85% of MCC and seems to play an important role in their pathogenesis. This new finding may help to develop new therapeutic options for MCC.