Augustin Toms, Bhende Siddharth, Chavda Keyur, VanderMeer Thomas, Cagir Burt
Department of General Surgery Residency, Robert Packer Hospital, One Guthrie Square, Sayre, PA 18840, USA.
J Gastrointest Surg. 2009 Jul;13(7):1306-12. doi: 10.1007/s11605-009-0875-x. Epub 2009 Apr 21.
Studies examining the relationship between computed tomography (CT) scans and appendiceal perforation have largely been conducted in urban centers. The present study sought to evaluate this relationship in a rural hospital.
This is a retrospective analysis of 445 patients who underwent appendectomies from January 2000 to June 2005 at a rural teaching hospital.
Four hundred forty-five patients were analyzed in two groups; those who underwent CT scans (N = 245) and those who did not (N = 200). Patients undergoing CT scans were significantly older (median age 38 vs. 22 years, P < 0.0001), were more likely to have perforated appendicitis (P 0.001), were less likely to undergo a negative appendectomy (P = 0.003), and had a significantly longer length of stay than those who did not (P 0.009). Analysis by gender showed that perforation rates continued to be significantly higher in males undergoing CT scans (P 0.004). To examine the possibility that sicker patients were more likely to receive CT scans and also be found to have perforated appendicitis, a sensitivity analysis was performed. Patients showing perforated appendicitis on initial CT scans were excluded and the analysis was repeated. The difference in perforation rates continued to remain significant (P 0.037).
Males undergoing CT scans are significantly more likely to have perforated appendicitis. A protocol-driven rational approach to CT evaluation of suspected appendicitis may lower perforation rates, especially in males.
关于计算机断层扫描(CT)与阑尾穿孔之间关系的研究大多在城市中心进行。本研究旨在评估农村医院中的这种关系。
这是一项对2000年1月至2005年6月在一家农村教学医院接受阑尾切除术的445例患者的回顾性分析。
445例患者被分为两组;接受CT扫描的患者(N = 245)和未接受CT扫描的患者(N = 200)。接受CT扫描的患者年龄显著更大(中位年龄38岁对22岁,P < 0.0001),更有可能患有穿孔性阑尾炎(P = 0.001),进行阴性阑尾切除术的可能性更小(P = 0.003),并且住院时间比未接受CT扫描的患者显著更长(P = 0.009)。按性别分析显示,接受CT扫描的男性穿孔率仍然显著更高(P = 0.004)。为了检验病情较重的患者更有可能接受CT扫描且也更有可能被发现患有穿孔性阑尾炎的可能性,进行了敏感性分析。排除初始CT扫描显示穿孔性阑尾炎的患者并重复分析。穿孔率的差异仍然显著(P = 0.037)。
接受CT扫描的男性患穿孔性阑尾炎的可能性显著更高。一种基于方案驱动的对疑似阑尾炎进行CT评估的合理方法可能会降低穿孔率,尤其是在男性中。