[薄叶石上莲中黄酮类成分研究]

[Flavonoid constituents from herbs of Sarcopyramis bodinieri var. delicata].

作者信息

Wan Chunpeng, Zheng Xiao, Chen Haifeng, Zou Xiuhong, Song Zirong, Zhou Shouran, Qiu Yan

机构信息

School of Medicine, Xiamen University, Xiamen 361005, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2009 Jan;34(2):172-4.

PMID:19385178

Abstract

Phytochemical studies of the the herb Sarcopyramis bodinieri var. delicate (Melastomataceae) have been carried out. The compounds were separated by repeated D101 macroporous adsorption resin column combined with Sephadex LH-20, ODS, and silica gel chromatgrophy. The structures were identified on the basis of extensive spectroscopic data analysis, and by comparison of their spectral data with those reported. Eight flavonoid compounds isolated from the ethyl acetate extract was identified as isorhamnetin (1), quercetin (2), isorhamnetin-3-O-beta-D-glucopyranoside (3), quercetin-3-O-beta-D-glucopyranoside (4), isorhamnetin-3-O-(6"-acetyl)-beta-D-glucopyranoside (5), isorhamnetin-3-O-(2"-acetyl)-beta-D-glucopyranoside (6), quercetin-3-O-(6"-acetyl)-beta-D-glucopyranoside (7), and quercetin- 3-O-(6"-O-E-p-coumaroyl)-beta-D-glucopyranoside (8). All of the compounds were separated from the genus of Sarcopyramis for the first time.

摘要

对秀丽野海棠（野牡丹科）全草进行了植物化学研究。化合物通过重复的D101大孔吸附树脂柱结合Sephadex LH - 20、ODS和硅胶柱色谱法进行分离。通过广泛的光谱数据分析，并将其光谱数据与已报道的数据进行比较来鉴定结构。从乙酸乙酯提取物中分离得到的8种黄酮类化合物被鉴定为异鼠李素（1）、槲皮素（2）、异鼠李素 - 3 - O - β - D - 吡喃葡萄糖苷（3）、槲皮素 - 3 - O - β - D - 吡喃葡萄糖苷（4）、异鼠李素 - 3 - O -（6″ - 乙酰基）- β - D - 吡喃葡萄糖苷（5）、异鼠李素 - 3 - O -（2″ - 乙酰基）- β - D - 吡喃葡萄糖苷（6）、槲皮素 - 3 - O -（6″ - 乙酰基）- β - D - 吡喃葡萄糖苷（7）和槲皮素 - 3 - O -（6″ - O - E - 对香豆酰基）- β - D - 吡喃葡萄糖苷（8）。所有这些化合物均首次从野海棠属中分离得到。