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罗杰·T·谢尔曼讲座。钝性胸主动脉损伤的治疗进展:从帕姆利时代至今。

Roger T. Sherman Lecture. Advances in the management of blunt thoracic aortic injury: Parmley to the present.

作者信息

Fabian Timothy C

机构信息

Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

出版信息

Am Surg. 2009 Apr;75(4):273-8.

Abstract

This article traces the evolution in management of blunt aortic injury (BAI) over the past 50 years from the time of the seminal description from Parmley in 1958. There have been major advances in both diagnostics and treatment paradigms with very rapid technologic advances occurring over the past decade. For many years, conventional aortography was the principle diagnostic tool, but it has been replaced by the progression of CT. The widespread adoption of antihypertensive therapy has sharply reduced the incidence of aortic rupture before planned reconstruction. Many patients with major associated injuries have definitive treatment of BAI managed in a delayed fashion with the use of hypertensives, which appears to improve outcomes. In the past 5 years, definitive treatment has changed with the majority of injuries being treated today with endoluminal stent grafts as opposed to open thoracotomy and traditional repair techniques. Paraplegia rates have diminished from 8 to 10 per cent down to 1 to 2 per cent in association with these therapeutic advances.

摘要

本文追溯了自1958年帕姆利首次描述钝性主动脉损伤(BAI)以来,过去50年中该疾病管理方法的演变。在过去十年中,随着技术的飞速发展,诊断和治疗模式都取得了重大进展。多年来,传统主动脉造影一直是主要的诊断工具,但现在已被CT的发展所取代。降压治疗的广泛应用显著降低了计划重建前主动脉破裂的发生率。许多伴有严重相关损伤的患者通过使用降压药物,以延迟方式对BAI进行确定性治疗,这似乎改善了治疗效果。在过去5年中,确定性治疗发生了变化,如今大多数损伤采用腔内支架移植物治疗,而非开胸手术和传统修复技术。随着这些治疗进展,截瘫发生率已从8%至10%降至1%至2%。

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