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医源性肝门横断的肝移植

Liver transplantation for iatrogenic porta hepatis transection.

作者信息

Zaydfudim Victor, Wright J Kelly, Pinson C Wright

机构信息

Department of Surgery, Division of Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2730, USA.

出版信息

Am Surg. 2009 Apr;75(4):313-6.

Abstract

Iatrogenic porta hepatis transection is a rare but devastating surgical complication. There are no systematic studies examining the best treatment strategy in patients with this injury. We report two cases of transection of all three portal structures, one during an open right adrenalectomy and another during a laparoscopic cholecystectomy, both of which were transferred to our tertiary care center hours postinjury. Diagnostic imaging and exploration revealed nonsalvageable livers, and both patients underwent total hepatectomies and portocaval shunting. Donor livers were available 12 to 20 hours after United Network for Organ Sharing Status 1 listing and both patients survived their postoperative course with 2- and 6-year follow up to date. Two-stage total hepatectomy with portocaval shunting followed by liver transplantation should be considered for patients presenting with porta hepatis transection.

摘要

医源性肝门横断是一种罕见但极具破坏性的手术并发症。目前尚无系统研究探讨此类损伤患者的最佳治疗策略。我们报告两例所有三个肝门结构均被横断的病例,一例发生在开放性右肾上腺切除术中,另一例发生在腹腔镜胆囊切除术中,两例均在受伤数小时后被转至我们的三级医疗中心。诊断性影像学检查和探查显示肝脏无法挽救,两名患者均接受了全肝切除术和门腔分流术。在器官共享联合网络1级登记后12至20小时获得供体肝脏,两名患者术后均存活,至今分别有2年和6年的随访。对于出现肝门横断的患者,应考虑行两阶段全肝切除术加门腔分流术,随后进行肝移植。

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