Loubignac Francois, Bourtoul Christophe, Chapel Francoise
Orthopaedic and traumatology Surgery A, Font-Pré Hospital, Toulon, France.
World J Surg Oncol. 2009 Apr 22;7:42. doi: 10.1186/1477-7819-7-42.
Lipoma is by far the most common of all benign soft-tissue tumors which far outnumber malignant tumors. Soft-tissue sarcomas are malignant tumors and are usually named for the type of tissue in which they begin. Liposarcoma (LPS), which arises in the fatty tissue, is rather an uncommon soft-tissue tumor. Multiple histologic subtypes of liposarcoma are recognized, including myxoid liposarcoma, and correspond to tumors of very different prognosis. In two-third of the cases, this tumor occurs in the muscle while often demonstrating a misleading benign appearance as observed in the majority of soft-tissue sarcomas.
We report the case of a 50-year-old man operated on for a fat tumor of the thigh initially diagnosed as lipoma but revealing to be a myxoid liposarcoma after histopathological examination. The initial incomplete tumor excision required the need for a re-excision with adjuvant chemotherapy and complementary radiotherapy.
When any suspicious soft-tissue tumor is diagnosed, the combined information gathered from accurate preoperative radiographic planning and X-rays or surgical biopsy is of tremendous value for establishing the most appropriate therapeutic program, highly adapted to the histopathological findings.
脂肪瘤是目前所有良性软组织肿瘤中最常见的，其数量远远超过恶性肿瘤。软组织肉瘤是恶性肿瘤，通常根据其起源的组织类型命名。脂肪肉瘤（LPS）起源于脂肪组织，是一种相当罕见的软组织肿瘤。脂肪肉瘤有多种组织学亚型，包括黏液样脂肪肉瘤，且对应着预后差异很大的肿瘤。在三分之二的病例中，这种肿瘤发生在肌肉中，同时在大多数软组织肉瘤中，它常常表现出具有误导性的良性外观。
我们报告了一例50岁男性患者，其大腿部的脂肪肿瘤最初被诊断为脂肪瘤，但经组织病理学检查后发现是黏液样脂肪肉瘤。最初的肿瘤切除不完全，因此需要再次切除，并辅以化疗和补充放疗。
当诊断出任何可疑的软组织肿瘤时，从准确的术前影像学规划以及X线检查或手术活检中收集到的综合信息，对于制定最适合组织病理学检查结果的治疗方案具有巨大价值。
