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吸烟相对强化作用随初始戒烟情况的变化。

Changes in the relative reinforcing effects of cigarette smoking as a function of initial abstinence.

作者信息

Yoon Jin H, Higgins Stephen T, Bradstreet Matthew P, Badger Gary J, Thomas Colleen S

机构信息

Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.

出版信息

Psychopharmacology (Berl). 2009 Aug;205(2):305-18. doi: 10.1007/s00213-009-1541-4. Epub 2009 Apr 24.

Abstract

RATIONALE

Experimental research is needed in investigating how early smoking abstinence affects relapse risk.

OBJECTIVE

The present study assessed the feasibility of promoting smoking abstinence using once- rather than thrice-daily abstinence monitoring and the relationship between different durations of initial abstinence and changes in smoking preference.

METHODS

Participants were 34 adult smokers randomized into one of two conditions: 14-day (14C) and 1-day (1C) contingent payment for smoking abstinence. Smoking status and participant ratings were assessed daily; a delay discounting task involving hypothetical money and an inter-temporal choice task involving hypothetical money and cigarettes were administered at baseline and days 7 and 14; a direct test of preference for smoking versus money was assessed on day 14.

RESULTS

Once-daily monitoring gained robust experimental control over smoking abstinence. No differences in delay discounting for hypothetical money were observed between the two conditions. Compared to the 1C condition, participants in the 14C condition (1) showed significant increases in the mean percent of delayed hypothetical money over cigarettes choices in the inter-temporal choice task, (2) were significantly less likely to ever choose the smoking option in the direct test of preference for smoking versus money, and (3) reported greater ease of abstaining from smoking and lower nicotine withdrawal and craving.

CONCLUSIONS

These results offer a more efficient procedure for experimentally promoting smoking abstinence, while providing further evidence that an initial period of sustained abstinence produces a profile of changes consistent with an overall lowering of relapse risk.

摘要

理论依据

需要进行实验研究来调查早期戒烟如何影响复吸风险。

目的

本研究评估了使用每日一次而非每日三次的戒烟监测来促进戒烟的可行性,以及初始戒烟不同时长与吸烟偏好变化之间的关系。

方法

34名成年吸烟者被随机分为两种情况之一:14天(14C)和1天(1C)戒烟 contingent payment。每天评估吸烟状况和参与者评分;在基线、第7天和第14天进行涉及假设金钱的延迟折扣任务以及涉及假设金钱和香烟的跨期选择任务;在第14天评估对吸烟与金钱偏好的直接测试。

结果

每日一次的监测对戒烟获得了强有力的实验控制。两种情况之间在假设金钱的延迟折扣方面未观察到差异。与1C情况相比,14C情况的参与者(1)在跨期选择任务中延迟假设金钱选择超过香烟选择的平均百分比显著增加,(2)在吸烟与金钱偏好的直接测试中选择吸烟选项的可能性显著降低,并且(3)报告戒烟更容易,尼古丁戒断和渴望更低。

结论

这些结果为通过实验促进戒烟提供了一种更有效的程序,同时进一步证明了初始持续戒烟期会产生与总体降低复吸风险一致的一系列变化。

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