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延迟折扣预测孕妇产后复吸香烟的情况。

Delay discounting predicts postpartum relapse to cigarette smoking among pregnant women.

作者信息

Yoon Jin H, Higgins Stephen T, Heil Sarah H, Sugarbaker Rena J, Thomas Colleen S, Badger Gary J

机构信息

Department of Psychiatry, University of Vermont, Burlington, VT, USA.

出版信息

Exp Clin Psychopharmacol. 2007 Apr;15(2):176-86. doi: 10.1037/1064-1297.15.2.186.

Abstract

Delay discounting (DD), a measure of impulsivity, describes the rate at which rewards lose value as the delay to their receipt increases. Greater discounting has been associated with cigarette smoking and various other types of drug abuse in recent research. The present study examined whether DD predicts treatment outcome among cigarette smokers. More specifically, the authors examined whether baseline discounting for hypothetical monetary rewards predicted smoking status at 24 weeks postpartum among women who discontinued smoking during pregnancy. Participants were 48 pregnant women (10.5 = 4.1 weeks gestational age at study entry) who participated in a clinical trial examining the use of incentives to prevent postpartum relapse. Several sociodemographic characteristics (being younger, being less educated, and reporting a history of depression) assessed at study entry were associated with increased baseline DD, but in multivariate analyses only DD predicted smoking status at 24 weeks postpartum. Greater baseline DD was a significant predictor of smoking status at 24 weeks postpartum. DD was reassessed periodically throughout the study and did not significantly change over time among those who eventually resumed smoking or those who sustained abstinence. The results extend the association of DD with risk for substance abuse to pregnant and recently postpartum cigarette smokers and demonstrate a significant relationship between DD and treatment outcome.

摘要

延迟折扣(DD)是一种冲动性的衡量指标,它描述了随着奖励获得延迟时间的增加,奖励价值衰减的速率。在最近的研究中,更高的折扣率与吸烟及其他各类药物滥用相关。本研究考察了延迟折扣是否能预测吸烟者的治疗结果。更具体地说,作者们考察了对于假设性金钱奖励的基线折扣率是否能预测孕期戒烟的女性在产后24周时的吸烟状况。研究对象为48名孕妇(研究开始时的孕周为10.5±4.1周),她们参与了一项关于使用激励措施预防产后复吸的临床试验。研究开始时评估的一些社会人口学特征(年龄较小、受教育程度较低以及有抑郁症病史)与基线延迟折扣率的增加相关,但在多变量分析中,只有延迟折扣率能预测产后24周时的吸烟状况。更高的基线延迟折扣率是产后24周时吸烟状况的显著预测指标。在整个研究过程中,延迟折扣率会定期重新评估,最终复吸者或持续戒烟者的延迟折扣率并未随时间发生显著变化。这些结果将延迟折扣与药物滥用风险之间的关联扩展至孕期及近期产后的吸烟者,并证明了延迟折扣与治疗结果之间存在显著关系。

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