Ingsathit Atiporn, Woratanarat Patarawan, Anukarahanonta Tongtavuch, Rattanasiri Sasivimol, Chatchaipun Porntip, Wattayakorn Kanokporn, Lim Stephen, Suriyawongpaisal Paibul
Clinical Epidemiology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok 10400, Thailand.
Accid Anal Prev. 2009 May;41(3):474-8. doi: 10.1016/j.aap.2009.01.010. Epub 2009 Feb 15.
The objective of this study was to determine the prevalence of psychoactive drug and alcohol use among general drivers and predictors of the drug use in Thailand. One thousand six hundred and thirty-five motor vehicle drivers were randomly selected from five geographical regions of Thailand between December 2005 and May 2006. The prevalence of psychoactive drugs was determined using urine tests by gas chromatography/mass spectrometry (GC/MS). Among 1635 drivers, 5.5% were tested positive for breath alcohol with 2% having a level exceeding the legal limit (> or =50mg%). Psychoactive drug was presented in 158 (9.7%) urine samples for drug analysis. The top 3 most frequently detected licit drugs were antihistamines (2.0%), sedative cough suppressant (0.7%) and benzodiazepines (0.2%). Illicit drugs detected included amphetamine (1.8%), cannabis (1.1%), mitragynine (Kratom) (0.9%) and morphine (0.1%). Only type of driver (commercial/non-commercial) was a significant predictor with psychoactive drug use. The prevalence of psychoactive drug use among drivers not involved in road crashes in Thailand was not as low as an earlier study in Europe using objective measurements, particularly among commercial drivers. However, for illicit drugs, the prevalence detected in this study was lower than those of earlier studies from high-income countries.
本研究的目的是确定泰国普通驾驶员中精神活性药物和酒精的使用情况以及药物使用的预测因素。2005年12月至2006年5月期间,从泰国五个地理区域随机选取了1635名机动车驾驶员。使用气相色谱/质谱联用仪(GC/MS)通过尿液检测来确定精神活性药物的流行情况。在1635名驾驶员中,5.5%的呼气酒精检测呈阳性,其中2%的酒精含量超过法定限量(≥50mg%)。158份(9.7%)尿液样本中检测出精神活性药物用于药物分析。检测出的最常见的3种合法药物是抗组胺药(2.0%)、镇静性止咳药(0.7%)和苯二氮䓬类药物(0.2%)。检测出的非法药物包括苯丙胺(1.8%)、大麻(1.1%)、帽柱木碱( kratom)(0.9%)和吗啡(0.1%)。只有驾驶员类型(商业/非商业)是精神活性药物使用的显著预测因素。泰国未发生道路交通事故的驾驶员中精神活性药物的使用流行率并不像欧洲早期一项采用客观测量方法的研究那么低,尤其是在商业驾驶员中。然而,对于非法药物,本研究中检测出的流行率低于高收入国家早期研究的结果。