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我们的产时子宫外处理(EXIT)手术经验:病例系列

Our Experience with EXIT Procedures: A Case Series.

作者信息

Vaishnav Darshil, Gandhi Sachin, Bansode Snehpali

机构信息

Deenanath Mangeshkar Hospital, Pune, India.

Present Address: Bhailal Amin General Hospital, Vadodara, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5992-5996. doi: 10.1007/s12070-024-05034-7. Epub 2024 Sep 13.

DOI:10.1007/s12070-024-05034-7
PMID:39559001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11569093/
Abstract

Respiratory distress in neonates presents challenges necessitating immediate airway management. This case series explores two instances of Ex-Utero Intra Partum Procedure (EXIT) for newborns with congenital airway obstructions. Case 1 describes a 34-year-old gravida 2 para 1 at 35 + 1 weeks with micrognathia. Due to failed intubation, an EXIT tracheostomy was performed successfully within 18 min, maintaining foetal oxygenation through utero-placental circulation. Case 2 involves a 29-year-old primigravida at 34 + 1 weeks with Congenital High Airway Obstruction Syndrome (CHAOS), where a planned EXIT tracheostomy was executed. These cases highlight the crucial role of multidisciplinary teams comprising obstetricians, anaesthetists, neonatologists, and specialized surgeons. Discussion emphasizes early prenatal diagnosis, meticulous planning, and parental counselling. The EXIT procedure is crucial for various indications such as oropharyngeal masses and CHAOS. Challenges like fetal tissue pliability and maintaining utero-placental circulation are addressed. Early detection, pathology understanding, and thorough planning are vital for successful outcomes. Psychological support for parents and a multidisciplinary approach ensure optimal maternal and neonatal outcomes. This series underscores the significance of the EXIT procedure in managing neonatal airway emergencies, particularly in preterm births.

摘要

新生儿呼吸窘迫带来了需要立即进行气道管理的挑战。本病例系列探讨了两例针对患有先天性气道阻塞的新生儿的产时宫外治疗手术(EXIT)。病例1描述了一名34岁、孕2产1、孕35⁺¹周的产妇,患有小颌畸形。由于插管失败,在18分钟内成功进行了EXIT气管切开术,通过子宫 - 胎盘循环维持胎儿氧合。病例2涉及一名29岁、孕34⁺¹周的初产妇,患有先天性高位气道阻塞综合征(CHAOS),实施了计划性EXIT气管切开术。这些病例凸显了由产科医生、麻醉师、新生儿科医生和专科外科医生组成的多学科团队的关键作用。讨论强调了早期产前诊断、精心规划和对父母的咨询。EXIT手术对于诸如口咽肿块和CHAOS等各种适应症至关重要。解决了诸如胎儿组织柔韧性和维持子宫 - 胎盘循环等挑战。早期检测、病理理解和全面规划对于成功结果至关重要。对父母的心理支持和多学科方法可确保最佳的母婴结局。本系列强调了EXIT手术在处理新生儿气道紧急情况中的重要性,特别是在早产情况下。

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The Ex-utero intrapartum treatment procedure: a narrative review.子宫外产时治疗程序:一项叙述性综述。
Front Pediatr. 2025 Jul 17;13:1601963. doi: 10.3389/fped.2025.1601963. eCollection 2025.

本文引用的文献

1
Ex utero intrapartum treatment (EXIT) procedures.产时宫外治疗(EXIT)手术
Semin Pediatr Surg. 2019 Aug;28(4):150820. doi: 10.1053/j.sempedsurg.2019.07.003. Epub 2019 Jul 22.
2
The EXIT (ex-utero intrapartum treatment) procedure - from the paediatric ENT perspective.EXIT(产时宫外治疗)手术——从儿科耳鼻喉科角度看
Acta Otorhinolaryngol Ital. 2018 Oct;38(5):480-484. doi: 10.14639/0392-100X-1261. Epub 2017 Nov 30.
3
Obstetric hemorrhage during an EXIT procedure for severe fetal airway obstruction.用于严重胎儿气道阻塞的产时宫外手术中的产科出血。
Can J Anaesth. 2009 Jun;56(6):437-42. doi: 10.1007/s12630-009-9092-z. Epub 2009 Apr 25.
4
The ex utero intrapartum treatment (EXIT) procedure.产时宫外治疗(EXIT)手术
Semin Neonatol. 2003 Jun;8(3):207-14. doi: 10.1016/S1084-2756(03)00029-0.