Lee Mei-Ching, Hu Sindy, Chen Min-Chi, Shih Yi-Ching, Huang Yau-Li, Lee Shih-Hung
Department of Dermatology, Chang Gung Memorial Hospital, Taipei and Taoyuan, Taipei, Taiwan.
Dermatol Surg. 2009 Jun;35(6):929-32. doi: 10.1111/j.1524-4725.2009.01157.x. Epub 2009 Apr 21.
In recent years, using the 1,064-nm Q-switched neodymium-doped yttrium aluminium garnet (Nd:YAG) laser (QSNYL) with or without exogenous topical carbon solution application for facial skin rejuvenation has become popular in Southeast Asia, but there has not been any published clinical report discussing the rejuvenation effect of QSNYL for Asian patients.
To evaluate the efficacy of QSNYL in improvement of pore size, sebaceous secretion, skin texture, and skin tone of Asian patients. We also observed whether there is any enhancement of application of topical carbon solution before the therapy.
Twenty-four female patients completed four sessions of treatments at 4-week intervals. The assessment was evaluated by the patients, two independent physicians, and Canfield VISIA Complexion Analysis. In addition, we conducted a split-face study such that, in each case, topical carbon solution was applied to the right side of the face before the laser treatment.
All evaluations showed significant improvement in rejuvenation effect. There was no difference in improvement in skin texture even after the application of topical carbon solution in our split-face study.
The QSNYL is a safe and effective rejuvenation modality in Asian patients. Topical carbon solution application did not enhance laser efficacy.
近年来，使用1064纳米调Q掺钕钇铝石榴石（Nd:YAG）激光（QSNYL），无论是否外用碳溶液，用于面部皮肤年轻化在东南亚已变得流行，但尚无已发表的临床报告讨论QSNYL对亚洲患者的年轻化效果。
评估QSNYL改善亚洲患者毛孔大小、皮脂分泌、皮肤质地和肤色的疗效。我们还观察了治疗前外用碳溶液是否有增效作用。
24名女性患者每隔4周完成4次治疗。评估由患者、两名独立医生以及Canfield VISIA肤色分析进行。此外，我们进行了一项半脸研究，即每例患者在激光治疗前将外用碳溶液涂于面部右侧。
所有评估均显示年轻化效果有显著改善。在我们的半脸研究中，即使应用外用碳溶液后，皮肤质地的改善也没有差异。
QSNYL对亚洲患者是一种安全有效的年轻化治疗方式。外用碳溶液并未增强激光疗效。
