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肉毒杆菌毒素在莫氏手术中治疗腮腺导管损伤的应用及管理方案综述。

The use of botulinum toxin in the treatment of a parotid duct injury during Mohs surgery and review of management options.

作者信息

Krishnan Ravi S, Clark David P, Donnelly Heidi B

机构信息

Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

出版信息

Dermatol Surg. 2009 Jun;35(6):941-7. doi: 10.1111/j.1524-4725.2009.01159.x. Epub 2009 Apr 8.

Abstract

BACKGROUND

Aggressive skin cancers on the cheeks may involve the parotid duct. For such tumors to be successfully removed, at least part of the parotid duct must be excised as well. Failure to properly address parotid duct injuries that result from Mohs micrographic surgery exposes the patient to a variety of adverse sequelae.

OBJECTIVE

To discuss the various diagnostic and treatment options that should be considered when managing parotid duct injuries that result from skin cancer extirpation.

MATERIALS AND METHODS

We describe a patient who sustained a parotid duct injury after Mohs micrographic surgery for treatment of squamous cell carcinoma. The patient was treated with intraparotid injections of botulinum toxin.

RESULTS

Two weeks after treatment of the injury with botulinum toxin, the patient reported complete resolution of his symptoms.

CONCLUSION

If a parotid duct injury is diagnosed at the time of tumor extirpation, then surgical repair of the duct should be attempted, but if surgical repair is not possible or if an injury remains unrecognized until well after tumor extirpation, then surgery is not necessary. In such cases, conservative, nonsurgical measures, such as treatment with botulinum toxin, will provide excellent results.

摘要

背景

脸颊部侵袭性皮肤癌可能累及腮腺导管。要成功切除此类肿瘤,至少部分腮腺导管也必须切除。莫氏显微外科手术导致的腮腺导管损伤若处理不当,会使患者面临多种不良后果。

目的

探讨在处理皮肤癌切除术后腮腺导管损伤时应考虑的各种诊断和治疗选择。

材料与方法

我们描述了一名患者,其在接受莫氏显微外科手术治疗鳞状细胞癌后发生了腮腺导管损伤。该患者接受了腮腺内注射肉毒杆菌毒素治疗。

结果

肉毒杆菌毒素治疗损伤两周后,患者报告症状完全缓解。

结论

如果在肿瘤切除时诊断出腮腺导管损伤,应尝试对导管进行手术修复,但如果无法进行手术修复,或者损伤在肿瘤切除后很长时间才被发现,那么手术并非必要。在这种情况下,保守的非手术措施,如肉毒杆菌毒素治疗,将取得良好效果。

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