肉毒杆菌毒素：治疗唾液腺狭窄症状的非侵入性选择-病例报告。
Botulinum toxin: A noninvasive option for the symptomatic treatment of salivary gland stenosis - a case report.
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Georg August University, Goettingen, Germany.
出版信息
Head Neck. 2010 Jul;32(7):959-63. doi: 10.1002/hed.21150.
BACKGROUND
A man diagnosed with Stensen's duct stenosis exhibited recurrent parotid swelling, invariably during meals. Previous parotid duct dilations and percutaneous radiotherapy were ineffective. Botulinum toxin (BTX) injections were injected into the affected gland to regulate salivary flow and reduce parotid swelling.
METHODS
BTX (22.5 units) was injected into the affected gland. A second treatment with 30 units BTX was carried out 7 weeks later. Two further injections followed after 4 months, respectively. The results were scored by the patient and evaluated in an examination.
RESULTS
The patient reported the disappearance of parotid swelling after 2 weeks of injections. This effect was maintained for 5 weeks after the first treatment and for 4 months after the following 2 treatments. There were no side effects.
CONCLUSION
Here we introduce BTX as a therapeutic option for the treatment of salivary duct stenosis when other therapies are ineffective and before opting for gland extirpation.
背景
一名被诊断为 Stensen 管狭窄的男性患者表现为复发性腮腺肿胀，总是在进餐时发生。之前进行过腮腺管扩张和经皮放射治疗，但均无效。将肉毒毒素（BTX）注射到受影响的腺体中，以调节唾液流量并减少腮腺肿胀。
方法
将 BTX（22.5 单位）注射到受影响的腺体中。7 周后，进行了第二次 30 单位 BTX 的治疗。4 个月后，分别进行了另外两次注射。结果由患者评分，并在检查中进行评估。
结果
患者在注射后 2 周报告腮腺肿胀消失。这种效果在第一次治疗后持续 5 周，在随后的 2 次治疗后持续 4 个月。没有副作用。
结论
当其他治疗方法无效且在选择腺体切除之前，我们将 BTX 作为治疗唾液管狭窄的一种治疗选择。
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