Corcuff P, de Lacharrière O, Lévêque J L
Laboratoires de Recherche Avancée de L'Oréal, Aulnay-sous-Bois, France.
J Gerontol. 1991 Nov;46(6):M223-7. doi: 10.1093/geronj/46.6.m223.
The skin microrelief can be assessed in vivo using a noninvasive method based on the image analysis of negative replicas, shadowed by oblique illumination. This technique was used to study changes in the surface furrows of the human volar forearm, related to the degree of extension, in volunteers of three age groups. Results confirmed that the skin in elderly subjects can be characterized by the lack of one of the two perpendicular furrow orientations observed in the young. During extension of the arm, the response of the microrelief in young subjects was clearly different from that in the elderly. Young skin buffered strain through a progressive shift in line density and furrow depth from one orientation to the other, whereas in the elderly, a progressive rotation of the single furrow orientation occurred. These differences would appear to be related to changes in the architecture and physical properties of the dermis. Microrelief, in the elderly subjects, showed a mean line density of 24/cm, regardless of the degree of extension. This constancy may reflect the ultimate stage in the chronological aging of the skin and may be characteristic of a loosened and relaxed dermis.
可以使用一种基于对由斜射光投射阴影的阴性复制品进行图像分析的非侵入性方法在体内评估皮肤微纹理。该技术用于研究三个年龄组志愿者中与伸展程度相关的人类掌侧前臂表面皱纹的变化。结果证实，老年受试者的皮肤特征是缺乏在年轻人中观察到的两种垂直皱纹方向中的一种。在手臂伸展过程中，年轻受试者的微纹理反应与老年受试者明显不同。年轻皮肤通过线密度和皱纹深度从一个方向到另一个方向的逐渐变化来缓冲应变，而在老年人中，单一皱纹方向会逐渐旋转。这些差异似乎与真皮的结构和物理性质的变化有关。在老年受试者中，无论伸展程度如何，微纹理的平均线密度为24/厘米。这种恒定性可能反映了皮肤自然老化的最终阶段，可能是松弛真皮的特征。
