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黑升麻相关的严重肝炎:两例报告及使用建议。

Severe hepatitis associated with the use of black cohosh: a report of two cases and an advice for caution.

机构信息

Department of Internal Medicine, Clinique Saint Pierre, Ottignies, Belgium.

出版信息

Eur J Gastroenterol Hepatol. 2009 Aug;21(8):941-5. doi: 10.1097/MEG.0b013e3283155451.

DOI:10.1097/MEG.0b013e3283155451
PMID:19404202
Abstract

In spite of the fact that severe side effects have been reported, black cohosh [Actaea racemosa (syn. Cimifuga racemosa)] is likely to be one of the most popular herbs used in the treatment of postmenopausal symptoms and menstrual dysfunction. We report the cases of two patients, one with submassive liver necrosis and the other with chronic hepatitis most likely related to the use of two different preparations containing black cohosh. This represents another advice for caution concerning this popular preparation of inconsistent therapeutic value.

摘要

尽管有报道称其存在严重的副作用,但黑升麻(Actaea racemosa(同义词:Cimifuga racemosa))可能仍是治疗绝经后症状和月经功能障碍最常用的草药之一。我们报告了两例病例,一例为亚大块肝坏死,另一例为可能与使用两种不同的黑升麻制剂有关的慢性肝炎。这再次提醒人们注意这种流行制剂治疗价值不一致的问题,使用时应谨慎。

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