Lachaud S, Suissa L, Mahagne M-H
Unité neurovasculaire, hôpital Saint-Roch, CHU de Nice, 5, rue Pierre-Dévoluy, 06006 Nice cedex 1, France.
Rev Neurol (Paris). 2010 Jan;166(1):76-82. doi: 10.1016/j.neurol.2009.02.003. Epub 2009 Apr 29.
Various clinical manifestations can occur in syphilis, especially meningovascular syphilis. We report three cases of ischemic stroke related to meningovascular syphilis and HIV infection.
Three men, aged 30, 31 and 41, presented typical neurologic deficit leading to the diagnosis of ischemic stroke. Radiographic investigations showed internal carotid thrombosis in two patients, and a basilar stenosis in the third. CSF analysis and blood samples revealed meningovascular syphilis associated with HIV infection. The other explorations were normal.
Due to the reemergence of syphilis, search for Treponema pallidum infection should be systematic in young stroke victims.
梅毒可出现多种临床表现，尤其是脑膜血管梅毒。我们报告3例与脑膜血管梅毒和HIV感染相关的缺血性卒中病例。
3名男性，年龄分别为30岁、31岁和41岁，出现典型神经功能缺损，诊断为缺血性卒中。影像学检查显示，2例患者有颈内动脉血栓形成，第3例患者有基底动脉狭窄。脑脊液分析和血液样本显示为与HIV感染相关的脑膜血管梅毒。其他检查均正常。
由于梅毒再度出现，对于年轻的卒中患者，应系统筛查梅毒螺旋体感染。
