Hong Seong Su, Lee Chul, Lee Chang Hee, Park Mieon, Lee Moon Soon, Hong Jin Tae, Lee Heesoon, Lee Mi Kyeong, Hwang Bang Yeon
College of Pharmacy, Chungbuk National University, Cheongju, 361-763, Korea.
Arch Pharm Res. 2009 Apr;32(4):501-4. doi: 10.1007/s12272-009-1404-x. Epub 2009 Apr 29.
A new sesamin type furofuran lignan, (-)-sesamin-2,2'-diol (1), along with two known flavonoids (2 and 3) and three phenolic compounds (4-6) were isolated from the aerial parts of Isodon japonicus. The structures of these compounds were determined by analysis of spectroscopic data (1D-, 2D-NMR, HRMS and CD) and by comparison of the data with those of related metabolites.
从糙苏的地上部分分离出一种新的芝麻素型呋喃呋喃木脂素,(-)-芝麻素-2,2'-二醇(1),以及两种已知的黄酮类化合物(2和3)和三种酚类化合物(4-6)。通过光谱数据分析(一维、二维核磁共振、高分辨质谱和圆二色光谱)以及将数据与相关代谢物的数据进行比较,确定了这些化合物的结构。