Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany,
Genes Nutr. 2009 Jun;4(2):113-22. doi: 10.1007/s12263-009-0123-8. Epub 2009 Apr 30.
New 'omics' technologies are changing nutritional sciences research. They enable to tackle increasingly complex questions but also increase the need for collaboration between research groups. An important challenge for successful collaboration is the management and structured exchange of information that accompanies data-intense technologies. NuGO, the European Nutrigenomics Organization, the major collaborating network in molecular nutritional sciences, is supporting the application of modern information technologies in this area. We have developed and implemented a concept for data management and computing infrastructure that supports collaboration between nutrigenomics researchers. The system fills the gap between "private" storing with occasional file sharing by email and the use of centralized databases. It provides flexible tools to share data, also during experiments, while preserving ownership. The NuGO Information Network is a decentral, distributed system for data exchange based on standard web technology. Secure access to data, maintained by the individual researcher, is enabled by web services based on the the BioMoby framework. A central directory provides information about available web services. The flexibility of the infrastructure allows a wide variety of services for data processing and integration by combining several web services, including public services. Therefore, this integrated information system is suited for other research collaborations.
新的“组学”技术正在改变营养科学研究。它们使我们能够解决日益复杂的问题,但也增加了研究小组之间合作的需求。成功合作的一个重要挑战是管理和结构化地交换伴随数据密集型技术而来的信息。欧洲营养基因组组织(NuGO)是分子营养科学领域的主要合作网络,它正在支持在这一领域应用现代信息技术。我们已经开发并实施了一个数据管理和计算基础设施的概念,以支持营养基因组学研究人员之间的合作。该系统填补了“私人”存储与偶尔通过电子邮件共享文件之间的空白,也填补了集中式数据库的空白。它提供了灵活的数据共享工具,甚至在实验过程中也可以共享数据,同时保留所有权。NuGO 信息网络是一个基于标准网络技术的数据交换的去中心化、分布式系统。通过基于 BioMoby 框架的 Web 服务,可以实现对由个人研究人员维护的数据的安全访问。一个中央目录提供有关可用 Web 服务的信息。该基础设施的灵活性允许通过组合多个 Web 服务(包括公共服务)来进行各种数据处理和集成服务。因此,这个集成的信息系统适合于其他研究合作。