Yu Quan, Huang Rongfu, Li Lingfeng, Lin Lin, Hang Wei, He Jian, Huang Benli
The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
Anal Chem. 2009 Jun 1;81(11):4343-8. doi: 10.1021/ac900141z.
A compact high-irradiance laser ionization time-of-flight mass spectrometry system has been developed for the multielemental analysis of solids. Helium was introduced into the ion source as a buffer gas to cool high kinetic energy ions and suppress the interference of multicharged ions. A special pulse train repelling mode was used to achieve explicit spectra. Two quantitative methods are described for the laser ionization mass spectrometry in this paper. The first of these is the routine calibration curve quantitation, in which various matrix-matched standards are required; the second method, which is based on the uniform correlation between the signal and elemental concentration of different samples, is more convenient and covers a typical dynamic range of 6 orders. All the investigations and results indicate satisfactory performance of the newly developed instrument and its applicability for simultaneous multielemental analysis of solid samples.
已开发出一种紧凑的高辐照度激光电离飞行时间质谱系统，用于固体的多元素分析。将氦气作为缓冲气体引入离子源，以冷却高动能离子并抑制多电荷离子的干扰。采用特殊的脉冲序列排斥模式来获得清晰的光谱。本文描述了激光电离质谱的两种定量方法。第一种是常规校准曲线定量法，需要各种基体匹配的标准物质；第二种方法基于不同样品的信号与元素浓度之间的均匀相关性，更方便，且覆盖典型的6个数量级的动态范围。所有研究和结果表明，新开发的仪器性能令人满意，适用于固体样品的同时多元素分析。
