Key Laboratory of Analytical Science, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
Anal Chem. 2010 Mar 1;82(5):1949-53. doi: 10.1021/ac9026912.
The simultaneous determination of nonmetallic elements in solid samples is difficult owing to their discrepant physical and chemical properties. We developed a high-irradiance laser ionization orthogonal time-of-flight mass spectrometry (LI-O-TOFMS) system and applied it for the determination of nonmetallic elements in solids. Helium was used as the buffer gas at 250 Pa in the source chamber; the laser irradiance was about 7 x 10(10) W/cm(2). A series of artificial standards containing B, C, N, O, F, Si, P, S, Cl, As, Br, Se, I, and Te were used. Explicit spectra were obtained with only a little interference from gas species and doubly charged matrix ions. Standardless semiquantitative analysis could be accomplished with a novel sampling methodology to obtain near-uniform sensitivity coefficients for different elements. Limits of detection (LOD) at microgram per gram level and a dynamic range of 6 orders of magnitude were achieved for most nonmetallic elements.
由于其物理和化学性质的差异，同时测定固体样品中的非金属元素是很困难的。我们开发了一种高辐照度激光电离正交飞行时间质谱（LI-O-TOFMS）系统，并将其应用于固体中非金属元素的测定。在源室中，氦气以 250 Pa 的缓冲气体使用；激光辐照度约为 7 x 10(10) W/cm(2)。使用了一系列含有 B、C、N、O、F、Si、P、S、Cl、As、Br、Se、I 和 Te 的人工标准品。只有很少的气体物种和双电荷基质离子的干扰，就可以得到明确的光谱。通过一种新的采样方法可以实现无标准的半定量分析，从而获得不同元素的近乎均匀的灵敏度系数。对于大多数非金属元素，检测限（LOD）达到微克/克水平，动态范围达到 6 个数量级。
