Demestre Guasch X, Raspall Torrent F, Vila Cerén C, Sala Castellví P, Elizari Saco M J, Martínez-Nadal S, Pallás Ribes R
Servicio de Pediatría-Neonatología, SCIAS-Hospital de Barcelona, Grup Assistència, Barcelona, España.
An Pediatr (Barc). 2009 Mar;70(3):241-52. doi: 10.1016/j.anpedi.2008.10.020. Epub 2009 Feb 7.
gestational age and anthropometric measurements, i.e. weight, length and head circumference at birth, have all been used as predictors of neonatal morbidity-mortality and adult morbidity. Differences in ethnic or socioeconomic background of newborn cohorts, as well as methodological differences between studies limit the validity and application of current anthropometric curves across different populations. Thus, we conducted a study to obtain local reference data in a Hospital that had a medium-high socio-economic class population, probably different to others recently published in our geographic area, and to compare them.
Weight, length and head circumference at birth were retrospectively analysed in 31,397 live Caucasian neonates born at 23-42 weeks in SCIAS-Hospital de Barcelona between 1992 and 2006. Only single gestations were selected and no other exclusion by materno-fetal or neonatal pathology criteria were applied. Percentile values, mean and standard deviation for each anthropometric measurement were calculated according to gestational age and gender. They were compared with the results from recent publications of our geographic area.
Males were found to have significantly higher weight, length and head circumference values than females from 36 weeks. There was a trend towards higher values in our population when compared with others in our geographic area.
The influence of socioeconomic factors on fetal growth seems evident. Nevertheless, it is difficult to assume that the observed differences must be exclusively due to the population characteristics or the different methodologies in the selection of the sample. Thus, it is desirable to have anthropometric reference curves obtained from populations of surrounding areas, with epidemiological methodologies that might be more appropriate in identifying valid outcome predictors, and enable us to compare with others groups according to racial, socioeconomic and disease factors.
胎龄以及人体测量指标,即出生时的体重、身长和头围,均已被用作新生儿发病率 - 死亡率及成人发病率的预测指标。新生儿队列的种族或社会经济背景差异,以及研究之间的方法学差异,限制了当前人体测量曲线在不同人群中的有效性和应用。因此,我们开展了一项研究,以在一家社会经济阶层为中高的医院获取本地参考数据,该医院的人群可能与我们地理区域内最近发表的其他研究对象不同,并对这些数据进行比较。
对1992年至2006年期间在巴塞罗那SCIAS医院出生的31397例23 - 42周的白人活产新生儿的出生体重、身长和头围进行回顾性分析。仅选择单胎妊娠,且未根据母胎或新生儿病理标准进行其他排除。根据胎龄和性别计算每个人体测量指标的百分位数、均值和标准差。将其与我们地理区域最近发表的研究结果进行比较。
发现从36周起,男性的体重、身长和头围值显著高于女性。与我们地理区域的其他人群相比,我们的人群有值更高的趋势。
社会经济因素对胎儿生长的影响似乎很明显。然而,很难假定观察到的差异一定完全归因于人群特征或样本选择中的不同方法。因此,希望从周边地区人群获得人体测量参考曲线,采用可能更适合识别有效结局预测指标的流行病学方法,并使我们能够根据种族、社会经济和疾病因素与其他群体进行比较。