Jayakumar R, Rajkumar M, Freitas H, Sudheesh Kumar P T, Nair S V, Furuike T, Tamura H
Faculty of Chemistry, Materials and Bioengineering and High Technology Research Centre, Kansai University, Osaka 564-8680, Japan.
Int J Biol Macromol. 2009 Aug 1;45(2):135-9. doi: 10.1016/j.ijbiomac.2009.04.016. Epub 2009 May 3.
Carboxymethyl chitosan-graft-D-glucuronic acid (CMCS-g-D-GA) was prepared by grafting D-GA onto CMCS in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and then the membranes were made from it. In this work, the bioactivity studies of CMCS-g-D-GA membranes were carried out and then characterized by SEM, CLSM, XRD and FT-IR. The CMCS-g-D-GA membranes were found to be bioactive. The adsorption of Ni2+, Zn2+ and Cu2+ ions onto CMCS-g-D-GA membranes has also been investigated. The maximum adsorption capacity of CMCS-g-D-GA for Ni2+, Zn2+ and Cu2+ was found to be 57, 56.4 and 70.2 mg/g, respectively. Hence, these membranes were useful for tissue engineering, environmental and water purification applications.
在1-乙基-3-(3-二甲基氨基丙基)碳二亚胺(EDC)存在的情况下，通过将D-葡萄糖醛酸(D-GA)接枝到羧甲基壳聚糖(CMCS)上制备了羧甲基壳聚糖接枝D-葡萄糖醛酸(CMCS-g-D-GA)，然后用其制备膜。在这项工作中，对CMCS-g-D-GA膜进行了生物活性研究，然后通过扫描电子显微镜(SEM)、共聚焦激光扫描显微镜(CLSM)、X射线衍射(XRD)和傅里叶变换红外光谱(FT-IR)对其进行表征。发现CMCS-g-D-GA膜具有生物活性。还研究了Ni2+、Zn2+和Cu2+离子在CMCS-g-D-GA膜上的吸附情况。发现CMCS-g-D-GA对Ni2+、Zn2+和Cu2+的最大吸附容量分别为57、56.4和70.2 mg/g。因此，这些膜可用于组织工程、环境和水净化应用。
