Wu Min, Wu Ping, Liu Meifang, Xie Haihui, Jiang Yueming, Wei Xiaoyi
Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Tianhe District, Guangzhou 510650, China.
Phytochemistry. 2009 Apr;70(6):746-50. doi: 10.1016/j.phytochem.2009.03.018. Epub 2009 May 4.
Iridoid glycosides, 2',3',6'-tri-O-acetyl-4'-O-trans-p-(O-beta-d-glucopyranosyl)coumaroyl-7-ketologanin (1), 2'-O-caffeoylloganic acid (2), 2'-O-p-hydroxybenzoylloganic acid (3), 2'-O-trans-p-coumaroylloganic acid (4), and 2'-O-cis-p-coumaroylloganic acid (5), were isolated from whole plants of Gentiana loureirii along with six known iridoids, 7-ketologanin (6), loganin (7), loganic acid (8), sweroside, boonein, and isoboonein, and three other known compounds. Their structures were elucidated by spectroscopic means and chemical correlations. The isolated iridoids were evaluated for antibacterial and antioxidant activities, but were either inactive or very weakly active.
从龙胆全草中分离得到了环烯醚萜苷类化合物，2',3',6'-三-O-乙酰基-4'-O-反式-p-(O-β-D-吡喃葡萄糖基)香豆酰基-7-酮基裂环马钱子苷（1）、2'-O-咖啡酰基马钱子苷（2）、2'-O-对羟基苯甲酰基马钱子苷（3）、2'-O-反式-p-香豆酰基马钱子苷（4）和2'-O-顺式-p-香豆酰基马钱子苷（5），以及六种已知的环烯醚萜类化合物，7-酮基裂环马钱子苷（6）、马钱子苷（7）、马钱子酸（8）、獐牙菜苷、布氏獐牙菜苷和异布氏獐牙菜苷，还有其他三种已知化合物。通过光谱手段和化学关联对它们的结构进行了阐明。对分离得到的环烯醚萜类化合物进行了抗菌和抗氧化活性评估，但它们要么无活性，要么活性非常弱。
