Calatayud Maldonado V, Calatayud Pérez J B, Aso Escario J
Department of Neurosurgery, Hospital Clínico de Zaragoza, Spain.
J Neurol Sci. 1991 Jul;103 Suppl:S15-8. doi: 10.1016/0022-510x(91)90003-p.
A single blind randomized study has been conducted in 216 patients with severe or moderate head injury, with the aim of comparing the evolution of those that received only conventional treatment with the evolution of those treated with CDP-choline. Our results indicate that CDP-choline improves the global outcome of patients. We have found a trend towards a greater improvement in motor, cognitive and psychic alterations in the patients treated with CDP-choline, as well as a shortening of the stay in the hospital ward in the patients receiving this drug that initially presented with severe head injuries.
对216例重度或中度颅脑损伤患者进行了一项单盲随机研究，目的是比较仅接受常规治疗的患者与接受胞磷胆碱治疗的患者的病情发展。我们的结果表明，胞磷胆碱可改善患者的整体预后。我们发现，接受胞磷胆碱治疗的患者在运动、认知和精神方面的改善有更大的趋势，并且最初患有重度颅脑损伤且接受该药物治疗的患者在病房的住院时间缩短。
