Speight Paul M, Barrett A William
Department of Oral & Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield, United Kingdom.
Br J Oral Maxillofac Surg. 2009 Dec;47(8):587-93. doi: 10.1016/j.bjoms.2009.03.017. Epub 2009 May 5.
Salivary gland tumours are a relatively rare group of lesions best managed in specialist centres. We review some of the factors that influence their prognosis. Clinical stage is the most important, with large malignancies having a poor prognosis regardless of histological grade and other features such as perineural invasion. Even high grade neoplasms may do well when they are small. A helpful guide to the management of salivary cancers is the "4 cm" rule.
唾液腺肿瘤是一组相对罕见的病变,最好在专科中心进行治疗。我们回顾了一些影响其预后的因素。临床分期是最重要的,无论组织学分级和其他特征(如神经周围侵犯)如何,大的恶性肿瘤预后都很差。即使是高分级肿瘤,体积较小时预后也可能较好。“4厘米”规则是唾液腺癌治疗的一个有用指南。