Pottinger Audrey M, Trotman-Edwards Helen, Younger Novie
Department of Obstetrics, Gynaecology and Child Health, University of the West Indies, Kingston 7, Jamaica.
Gen Hosp Psychiatry. 2009 May-Jun;31(3):254-61. doi: 10.1016/j.genhosppsych.2009.02.002. Epub 2009 Mar 27.
Antenatal depression, despite its association with increased maternal morbidity risks, is understudied in the developing world. We determined the rate and predictors of depression throughout pregnancy and the use of medication in women attending an obstetric clinic.
Prospective longitudinal study of 452 women newly registered at the antenatal clinic at the University Hospital of the West Indies between September 2005 and February 2006. Sociodemographic data, clinical information and self reports of depression using Edinburgh Postnatal Depression Scale (EPDS) were gathered over three trimesters.
On average, 25% of women were identified as having a probable depressive disorder over the three trimesters. Independent demographic predictors were youth and unemployment (P<05). Planned pregnancy, exercising, not smoking, being married and support from physician and family were protective factors (P<.05). Using a multivariable model, prior history of depression was the strongest predictor of depression during pregnancy. Of those taking medication for depression prior to pregnancy, only 1.6% remained on medication during the pregnancy.
Poverty-related factors and lifestyle are associated with higher EPDS scores during pregnancy in Jamaican women. A protocol of psychosocial management in obstetric care is discussed along with recommendations for future research.
尽管产前抑郁症与孕产妇发病风险增加有关,但在发展中国家对其研究不足。我们确定了整个孕期抑郁症的发生率和预测因素,以及在一家产科诊所就诊的女性中药物使用情况。
对2005年9月至2006年2月期间在西印度群岛大学医院产前诊所新登记的452名女性进行前瞻性纵向研究。在三个孕期收集社会人口统计学数据、临床信息以及使用爱丁堡产后抑郁量表(EPDS)进行的抑郁自我报告。
平均而言,在三个孕期中,25%的女性被确定可能患有抑郁症。独立的人口统计学预测因素是年轻和失业(P<0.05)。计划怀孕、锻炼、不吸烟、已婚以及来自医生和家人的支持是保护因素(P<0.05)。使用多变量模型,既往抑郁症病史是孕期抑郁症最强的预测因素。在怀孕前服用抗抑郁药物的女性中,只有1.6%在孕期继续用药。
在牙买加女性中,与贫困相关的因素和生活方式与孕期较高的EPDS评分有关。讨论了产科护理中的心理社会管理方案以及对未来研究的建议。