Flynn Heather A, Blow Frederic C, Marcus Sheila M
University of Michigan Medical School, Ann Arbor, MI 48105, USA.
Gen Hosp Psychiatry. 2006 Jul-Aug;28(4):289-95. doi: 10.1016/j.genhosppsych.2006.04.002.
The purpose of this study was to provide information on rates of depression treatment among pregnant women at risk for depression and among those with clinician-diagnosed current major depressive disorder (MDD) and to examine predictors of depression treatment.
Women seeking prenatal care completed a screening survey (including the Center for Epidemiological Studies-Depression Scale) in several hospital-based obstetrics clinics. Women identified as high risk for depression completed diagnostic interviews (n=276) during pregnancy, consisting of the Structured Clinical Interview for DSM-IV, measures of depression symptom severity (Beck Depression Inventory-II), health functioning (SF-36) and current and past psychiatric treatment.
Among women with a current MDD diagnosis, most of whom were experiencing a recurrence, 33% were currently receiving any depression treatment. The presence of current MDD was not found to be related to use of treatment. Prior history of MDD, history of psychiatric treatment and depression severity were significant predictors of depression treatment during pregnancy.
Most women with current MDD were found to be either untreated or suboptimally treated, and prenatal MDD was not predictive of treatment. These findings point to the need for effective detection, targeted follow-up assessment and treatment linkage interventions to be studied in medical settings that encounter perinatal women.
本研究旨在提供有关有抑郁风险的孕妇以及临床诊断为当前患有重度抑郁症(MDD)的孕妇的抑郁症治疗率的信息,并研究抑郁症治疗的预测因素。
在几家医院的产科诊所,寻求产前护理的女性完成了一项筛查调查(包括流行病学研究中心抑郁量表)。被确定为抑郁症高风险的女性在孕期完成了诊断访谈(n = 276),包括DSM-IV结构化临床访谈、抑郁症状严重程度测量(贝克抑郁量表-II)、健康功能(SF-36)以及当前和过去的精神治疗情况。
在当前被诊断为MDD的女性中,大多数正在经历复发,其中33%目前正在接受任何抑郁症治疗。未发现当前患有MDD与治疗的使用有关。MDD既往史、精神治疗史和抑郁严重程度是孕期抑郁症治疗的重要预测因素。
发现大多数当前患有MDD的女性未接受治疗或治疗不充分,产前MDD不能预测治疗情况。这些发现表明,在接诊围产期女性的医疗机构中,需要研究有效的检测、有针对性的随访评估和治疗联系干预措施。