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表现为胰腺肿块的纤维板层癌:病例报告及文献复习

Fibrolamellar carcinoma presenting as a pancreatic mass: case report and review of the literature.

作者信息

Thirabanjasak Duangpen, Sosothikul Darintr, Mahayosnond Atchara, Thorner Paul S

机构信息

Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

J Pediatr Hematol Oncol. 2009 May;31(5):370-2. doi: 10.1097/MPH.0b013e3181984f7f.

Abstract

Fibrolamellar carcinoma is a subtype of hepatocellular carcinoma with distinct clinicopathologic features including presentation at a younger age. Although early studies suggested that fibrolamellar carcinoma had a better prognosis than conventional hepatocellular carcinoma, most later studies have found no difference. Patients often have lymph node metastases at presentation in addition to the hepatic primary. We describe an unusual case in a Thai boy who presented with a pancreatic mass that was clinically suspected to be a primary pancreatic tumor, but on biopsy was found to be metastatic fibrolamellar carcinoma. To our knowledge, this manner of presentation has not been previously reported for fibrolamellar carcinoma, nor has metastatic spread to the pancreas.

摘要

纤维板层癌是肝细胞癌的一种亚型,具有独特的临床病理特征,包括发病年龄较轻。尽管早期研究表明纤维板层癌的预后优于传统肝细胞癌,但大多数后续研究并未发现差异。患者除肝脏原发肿瘤外,就诊时往往已有淋巴结转移。我们描述了一名泰国男孩的罕见病例,他表现为胰腺肿块,临床怀疑是原发性胰腺肿瘤,但活检发现是转移性纤维板层癌。据我们所知,纤维板层癌此前尚未有过这种表现方式的报道,转移至胰腺的情况也未曾有过报道。

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