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位于腭部的神经鞘瘤:临床病例及文献综述

Schwannoma located in the palate: clinical case and literature review.

作者信息

López-Carriches Carmen, Baca-Pérez-Bryan Rafael, Montalvo-Montero Santiago

机构信息

Universidad Complutense de Madrid, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2009 Sep 1;14(9):e465-8.

Abstract

Schwannoma is a benign tumor that originates from the presence of Schwann cells of the peripheral nerves. They are usually asymptomatic, do not recur, and malignant transformation is rare. The preoperative diagnosis is often difficult, and although computed tomography and magnetic resonance imaging are very helpful, in the majority of cases, the diagnosis can only be made during surgery and by histological study. The immunohistochemistry reveals that the Schwannoma cells test positive for S-100 protein. We describe a clinical case of Schwannoma located in the palate of a 15-year-old patient. It is important to highlight that the Schwannoma is usually found in the head and neck, and rarely in the oral cavity. When it does occur in this area, it is more likely to be found in the tongue. Other locations in the oral cavity include: the floor of the mouth, palate, gingiva, vestibular mucosa, lips and mental nerve area, listed from most common to least common. There has been no sign of recurrence two years after surgery.

摘要

神经鞘瘤是一种起源于周围神经施万细胞的良性肿瘤。它们通常无症状,不复发,恶变罕见。术前诊断往往困难,尽管计算机断层扫描和磁共振成像非常有帮助,但在大多数情况下,只有在手术期间并通过组织学研究才能做出诊断。免疫组织化学显示神经鞘瘤细胞对S-100蛋白检测呈阳性。我们描述了一例位于一名15岁患者腭部的神经鞘瘤临床病例。需要强调的是,神经鞘瘤通常见于头颈部,很少见于口腔。当它出现在该区域时,更有可能见于舌头。口腔中的其他部位包括:从最常见到最不常见依次为口底、腭、牙龈、前庭黏膜、嘴唇和颏神经区。手术后两年没有复发迹象。

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