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头颈部神经鞘瘤的流行病学、临床及组织病理学特征——我们在罗马尼亚西部的经验及手术见解

Epidemiological, Clinical, and Histopathological Features of the Head and Neck Region Schwannomas-Our Experience in the Western Part of Romania with Surgical Insights.

作者信息

Nicoara Adrian, Rakitovan Marina, Closca Raluca Maria, Militaru Marius, Cindrea Alexandru-Cristian, Zara Flavia

机构信息

Discipline of Dentoalveolar Surgery, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

Oro-Maxillo-Facial Surgery Clinic, Emergency City Hospital, 300062 Timisoara, Romania.

出版信息

Diagnostics (Basel). 2024 Oct 20;14(20):2334. doi: 10.3390/diagnostics14202334.

Abstract

INTRODUCTION

Schwannomas are benign solitary, slow-growing, encapsulated, asymptomatic tumors arising from Schwann's sheath of nervous fibers.

OBJECTIVES

The current paper presents all the cases diagnosed with different types of schwannomas in the head and neck region between January 2009 and December 2023 in the Western part of Romania. In this period, ten cases of schwannoma were identified.

MATERIALS AND METHODS

The pathological exams were performed at the Department of Pathology using morphological Hematoxylin-Eosin staining. In addition, immunohistochemical reactions were used in order to confirm the diagnosis.

RESULTS

Demographic and clinical data, imaging features, surgical approach, and morphological and immunohistochemical aspects are presented. The results also display an impressive clinical picture of a gigantic ancient schwannoma.

CONCLUSIONS

This retrospective study describes our experience with head and neck schwannomas, the diagnostic methods available, the surgical decisions, and the histopathological aspects while analyzing the data and reviewing the published specialized literature in the English language.

摘要

引言

施万细胞瘤是起源于神经纤维施万鞘的良性、孤立性、生长缓慢、有包膜且无症状的肿瘤。

目的

本文介绍了2009年1月至2023年12月期间罗马尼亚西部诊断出的所有头颈部不同类型施万细胞瘤病例。在此期间,共确诊10例施万细胞瘤。

材料与方法

病理检查在病理科采用苏木精-伊红形态学染色进行。此外,还采用免疫组化反应来确诊。

结果

呈现了人口统计学和临床数据、影像学特征、手术方式以及形态学和免疫组化方面的情况。结果还展示了一例巨大陈旧性施万细胞瘤令人印象深刻的临床表现。

结论

这项回顾性研究描述了我们在头颈部施万细胞瘤方面的经验、可用的诊断方法、手术决策以及组织病理学方面的情况,同时分析数据并查阅了英文发表的专业文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40db/11506826/47937b467700/diagnostics-14-02334-g001.jpg

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