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耳廓神经鞘瘤:1例罕见病例报告及现有文献综述

Auricle Schwannoma: Presentation of a Rare Case and Review of Existing Literature.

作者信息

Dokania Vivek, Mayashankar Vishwakarma, Kothari Shikha, Doiphode Ajay, Bhargava Samir, Garg Aditi

机构信息

Department of Otolaryngology- Head and Neck Surgery, HBT Medical College and Dr RN Cooper Municipal General Hospital, Juhu, Mumbai, Maharashtra 400056 India.

Department of Otolaryngology- Head and Neck Surgery, HBT Medical College and HBT Trauma Municipal Hospital, Jogeshwari, Mumbai, Maharashtra 400060 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2021 Dec;73(4):523-529. doi: 10.1007/s12070-020-01953-3. Epub 2020 Jul 11.

Abstract

Schwannomas are extremely rare over auricle. Despite the extensive somatogenic neural innervations of the pinna, schwannomas are never amongst the differentials for a benign auricular mass. Previously published articles have all agreed on the rarity of this lesion occurring over the auricle. However, none of the articles have tackled and extensively reviewed the auricle schwannomas (AS) as an individual entity. The article aim to review previously published cases of AS along with an illustrative case, and provide a better insight regarding demographic, clinicopathological and immunohistochemical features of this neural tumor in a rare site. A systemic review of English literature was performed after using a sensitive search strategy involving three different databases (PubMed, Google Scholar and Embase). A total of nine cases were included. They mostly presented in young adults as a slow growing tumor (mean duration: 3.17 years) and showed a slightly higher male predominance (male/female ratio 1.25:1). They were mostly located over lateral surface (66.67%) with a predilection for left ear (77.78%). Conventional histological variant has only been reported. Complete surgical excision was performed for all the cases without any reports of recurrence or malignant transformation. AS present as a solitary, painless, firm and well-encapsulated lesion, mostly over the lateral auricle surface. Preoperative clinical diagnosis is difficult and radiological investigations do not hold much importance. FNAC is inconclusive and diagnosis mandates histopathologic examination. The nerve of tumor origin is difficult to precisely identify. Complete surgical excision is the treatment of choice. Post-operative prognosis is excellent.

摘要

耳郭神经鞘瘤极为罕见。尽管耳廓有广泛的体神经支配,但神经鞘瘤从未被列入良性耳廓肿物的鉴别诊断范围。此前发表的文章均认同这种病变在耳廓发生的罕见性。然而,尚无文章将耳廓神经鞘瘤(AS)作为一个独立实体进行深入探讨和全面综述。本文旨在回顾既往发表的AS病例及一个典型病例,并对这种罕见部位神经肿瘤的人口统计学、临床病理和免疫组化特征提供更深入的见解。采用涉及三个不同数据库(PubMed、谷歌学术和Embase)的敏感检索策略,对英文文献进行了系统综述。共纳入9例病例。它们大多在年轻人中表现为生长缓慢的肿瘤(平均病程:3.17年),男性略占优势(男/女比例为1.25:1)。它们大多位于外侧表面(66.67%),以左耳居多(77.78%)。仅报道了传统组织学变异型。所有病例均行完整手术切除,无复发或恶变报道。AS表现为孤立、无痛、质地硬且包膜完整的肿物,大多位于耳廓外侧表面。术前临床诊断困难,影像学检查意义不大。细针穿刺抽吸活检(FNAC)结果不明确,诊断需依靠组织病理学检查。肿瘤起源的神经难以精确识别。完整手术切除是首选治疗方法。术后预后良好。

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Auricle Schwannoma: Presentation of a Rare Case and Review of Existing Literature.耳廓神经鞘瘤:1例罕见病例报告及现有文献综述
Indian J Otolaryngol Head Neck Surg. 2021 Dec;73(4):523-529. doi: 10.1007/s12070-020-01953-3. Epub 2020 Jul 11.
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本文引用的文献

1
Palatal Schwannoma: An Analysis of 45 Literature Reports and of an Illustrative Case.腭部神经鞘瘤:45篇文献报道及1例病例分析
Int Arch Otorhinolaryngol. 2019 Jul;23(3):e360-e370. doi: 10.1055/s-0039-1692635. Epub 2019 Jul 26.
3
Schwannoma of the external auditory canal: An exceptional site.外耳道神经鞘瘤:一个特殊的部位。
Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Jun;136(3):211-213. doi: 10.1016/j.anorl.2019.02.014. Epub 2019 Mar 12.
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Massive Schwannoma Originating From the External Auditory Canal Invading the Mastoid.
Ear Nose Throat J. 2019 Jan;98(1):25-27. doi: 10.1177/0145561318824808. Epub 2019 Jan 30.
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Clinical analysis of auricular benign masses.耳部良性肿物的临床分析
Korean J Audiol. 2012 Apr;16(1):10-3. doi: 10.7874/kja.2012.16.1.10. Epub 2012 Apr 30.
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Schwannoma of the hard palate.硬腭神经鞘瘤。
Indian J Otolaryngol Head Neck Surg. 2009 Jan;61(Suppl 1):52-4. doi: 10.1007/s12070-009-0018-4. Epub 2009 Mar 21.

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