Gundling N, Drews S, Hoedemaker M
Production Medicine Unit, Clinic for Cattle, University of Veterinary Medicine Hannover, Hannover, Germany.
Reprod Domest Anim. 2015 Dec;50(6):893-900. doi: 10.1111/j.1439-0531.2009.01342.x. Epub 2009 Mar 11.
It was the aim of this field study to evaluate two different protocols of ovulation synchronization for the treatment of ovarian cysts and their effect on reproductive performance in dairy cows. In addition, factors with a possible influence on treatment success and pregnancy outcome as well as costs per pregnancy were analysed. The study was performed with 130 German Holsteins with ovarian cysts diagnosed on days 55 to 60 postpartum. Cows belonging to group 1 (n = 65) received a modified ovsynch protocol [day 0: 0.15 mg cloprostenol (PGF) + 0.02 mg buserelin acetate (GnRH); day 14: PGF; day 16: GnRH]. Group 2 (n = 65) was treated with the conventional ovsynch protocol (day 0: GnRH; day 7: PGF; day 9: GnRH). Timed artificial insemination was performed 20 to 24 h later. Cows without ovarian cysts served as controls. Treatment success (disappearance of the ovarian cyst) after the first ovsynch cycle was higher in group 1 (66.2%) than in group 2 (23.1%, p < 0.05). Reproductive measures in group 1 were comparable with those of the control group and, compared with group 2, were conspicuously better (66.2%, 76.9%, 83.1%, 59.5% vs. 40.0%, 50.7%, 60.0%, 27.5% for cumulative pregnancy rate after treatment cycle 1 to 3 and second service conception rate, respectively, p < 0.05). Overconditioned cows and cows with larger ovarian cysts showed a diminished treatment and pregnancy success. In group 1, costs per pregnancy were only slightly higher than in the control group (group 1: €352.44, group 2: €484.59, control group: €333.77). In conclusion, our results suggest that ovsynch protocols can be used in the treatment of ovarian cysts. The modified ovsynch protocol led to a better cure rate as well as a better reproductive performance, and was economically beneficial compared with a conventional ovsynch protocol.
本田间研究的目的是评估两种不同的排卵同步方案对奶牛卵巢囊肿的治疗效果及其对繁殖性能的影响。此外，还分析了可能影响治疗成功率和妊娠结局的因素以及每次妊娠的成本。该研究对130头产后55至60天被诊断为卵巢囊肿的德国荷斯坦奶牛进行。第1组（n = 65）的奶牛接受改良的同期发情方案[第0天：0.15 mg氯前列醇（PGF）+ 0.02 mg醋酸布舍瑞林（GnRH）；第14天：PGF；第16天：GnRH]。第2组（n = 65）采用传统的同期发情方案（第0天：GnRH；第7天：PGF；第9天：GnRH）。20至24小时后进行定时人工授精。无卵巢囊肿的奶牛作为对照。第1组在第一个同期发情周期后的治疗成功率（卵巢囊肿消失）高于第2组（66.2%对23.1%，p < 0.05）。第1组的繁殖指标与对照组相当，与第2组相比明显更好（治疗周期1至3后的累积妊娠率和第二次输精受胎率分别为66.2%、76.9%、83.1%、59.5%对40.0%、50.7%、60.0%、27.5%，p < 0.05）。过度肥胖的奶牛和卵巢囊肿较大的奶牛治疗成功率和妊娠成功率较低。在第1组中，每次妊娠的成本仅略高于对照组（第1组：352.44欧元，第2组：484.59欧元，对照组：333.77欧元）。总之，我们的结果表明，同期发情方案可用于治疗卵巢囊肿。改良的同期发情方案导致更好的治愈率以及更好的繁殖性能，与传统的同期发情方案相比在经济上更具优势。
