通过拉曼光谱对声悬浮液滴进行化学分析。

Tuckermann Rudolf, Puskar Ljiljana, Zavabeti Mahta, Sekine Ryo, McNaughton Don

Institute of Physical Chemistry, University of Göttingen, Tamannstr. 6, 37077 Göttingen, Germany.

Anal Bioanal Chem. 2009 Jul;394(5):1433-41. doi: 10.1007/s00216-009-2800-2. Epub 2009 May 6.

An experimental apparatus combining Raman spectroscopy with acoustic levitation, Raman acoustic levitation spectroscopy (RALS), is investigated in the field of physical and chemical analytics. Whereas acoustic levitation enables the contactless handling of microsized samples, Raman spectroscopy offers the advantage of a noninvasive method without complex sample preparation. After carrying out some systematic tests to probe the sensitivity of the technique to drop size, shape, and position, RALS has been successfully applied in monitoring sample dilution and preconcentration, evaporation, crystallization, an acid-base reaction, and analytes in a surface-enhanced Raman spectroscopy colloidal suspension.

一种将拉曼光谱与声悬浮相结合的实验装置——拉曼声悬浮光谱（RALS），在物理和化学分析领域得到了研究。声悬浮能够实现对微米级样品的非接触式处理，而拉曼光谱则具有无需复杂样品制备的非侵入性方法的优势。在进行了一些系统测试以探究该技术对液滴大小、形状和位置的灵敏度之后，拉曼声悬浮光谱已成功应用于监测样品稀释和预浓缩、蒸发、结晶、酸碱反应以及表面增强拉曼光谱胶体悬浮液中的分析物。