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中国系统性红斑狼疮患者的抗心磷脂抗体和狼疮抗凝物

Anticardiolipin antibodies and lupus anticoagulant in Chinese patients with systemic lupus erythematosus.

作者信息

Wong K L, Liu H W, Ho K, Chan K, Wong R

机构信息

Department of Medicine and Pathology, Queen Mary Hospital, University of Hong Kong.

出版信息

J Rheumatol. 1991 Aug;18(8):1187-92.

PMID:1941822
Abstract

Ninety-one consecutive patients with systemic lupus erythematosus (SLE) were studied. Forty-two patients had positive anticardiolipin antibodies (aCl) 40 aCl-IgG (44.4%); 4 aCl-IgA (4.4%); 1 aCl-IgM (1.1%). One patient had both aCl-IgG and aCl-IgA and 1 patient had aCl-IgG, aCl-IgA and aCl-IgM. Ten patients (11.1%) had lupus anticoagulant (LA). Both aCl isotypes and LA had no statistical association with thrombosis or thrombocytopenia.

摘要

对91例连续性系统性红斑狼疮(SLE)患者进行了研究。42例患者抗心磷脂抗体(aCl)呈阳性,其中40例为aCl-IgG(44.4%);4例为aCl-IgA(4.4%);1例为aCl-IgM(1.1%)。1例患者同时有aCl-IgG和aCl-IgA,1例患者同时有aCl-IgG、aCl-IgA和aCl-IgM。10例患者(11.1%)有狼疮抗凝物(LA)。aCl各亚型和LA与血栓形成或血小板减少均无统计学关联。

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引用本文的文献

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Clinical significance of IgA anti-cardiolipin and IgA anti-β2glycoprotein I antibodies.IgA 抗心磷脂抗体和 IgA 抗β2 糖蛋白 I 抗体的临床意义。
Curr Rheumatol Rep. 2013 Jul;15(7):343. doi: 10.1007/s11926-013-0343-1.
2
Ethnic and geographical variation in antiphospholipid (Hughes) syndrome.抗磷脂(休斯)综合征的种族和地理差异。
Ann Rheum Dis. 2005 Dec;64(12):1671-6. doi: 10.1136/ard.2005.038448. Epub 2005 May 26.