Faculty of Arts & Sciences, Department of Biology, Pamukkale University, Kinikli Campus, Kinikli, Denizli, Turkey.
Environ Monit Assess. 2010 Jun;165(1-4):87-96. doi: 10.1007/s10661-009-0928-3. Epub 2009 May 6.
Pollution of the aquatic environment is a global concern owing to the devastating effects of contaminants whose levels are growing at an alarming rate, and it has become a major threat for marine organisms, as well as to humans as consumers. This study has been carried out on leaping mullet obtained from Aliaga Bay, which is located on the west coast of the Aegean Sea near Izmir and hosts the world's fifth largest shipyard, plus a broad range of industrial activities, including an oil refinery and a paper factory. The waste from these industries, combined with municipal sewer discharges, is the main cause of pollution in this region. There is no national documentation or research on the determination of pollution resulting from the industrial activities in this area. In the present study, the degree of induction of CYP4501A-associated 7-ethoxyresorufin O-deethylase (EROD) activity and immunochemical detection of CYP1A1 in the liver of leaping mullet (Lisa saliens) were used as biomarkers for the assessment of polycyclic aromatic hydrocarbon (PAH)-type organic pollutants in Aliaga Bay. Mullet caught from different locations of the bay had approximately 52 times more EROD activity than the feral fish sampled from a clean reference site near Foca, Izmir. The results of this study indicate that Aliaga Bay is highly contaminated with PAH-type organic pollutants.
水环境污染是一个全球性的问题，因为污染物的水平正在以惊人的速度增长，其破坏性影响令人担忧，这已经对海洋生物以及作为消费者的人类构成了重大威胁。本研究以阿里亚加湾（位于爱琴海西海岸伊兹密尔附近）捕获的跳鲈为研究对象，该海湾拥有世界第五大造船厂，以及广泛的工业活动，包括炼油厂和造纸厂。这些工业的废物加上城市污水排放是该地区污染的主要原因。该地区工业活动造成的污染程度尚无国家文件或研究记载。在本研究中，使用 CYP4501A 相关的 7-乙氧基荧蒽 O-脱乙基酶（EROD）活性诱导程度和肝 CYP1A1 的免疫化学检测作为阿里亚加湾多环芳烃（PAH）型有机污染物评估的生物标志物。从海湾不同地点捕获的跳鲈的 EROD 活性比从伊兹密尔附近福卡（Foca）清洁参考点采集的野生鱼类高约 52 倍。本研究结果表明，阿里亚加湾受到 PAH 型有机污染物的高度污染。
