Heagerty A M
Department of Medicine, University Hospital of South Manchester, West Didsbury, UK.
J Hum Hypertens. 1991 Aug;5 Suppl 1:3-8.
Hypertension has emerged as an important risk factor in cardiovascular diseases. However, the success of antihypertensive treatment in reducing cardiac mortality is limited. It is becoming clear that structural changes in the resistance vessels and, indeed, other vascular changes such as hypertrophy in the aorta and left ventricle increase the risk of premature cardiac events. Future therapy for hypertension must be directed at not only lowering blood pressure but also reversing structural alterations in the vasculature.
高血压已成为心血管疾病的一个重要危险因素。然而，抗高血压治疗在降低心脏死亡率方面的成效有限。越来越明显的是，阻力血管的结构变化以及主动脉和左心室肥大等其他血管变化会增加心脏过早发病的风险。未来的高血压治疗不仅必须着眼于降低血压，还必须扭转血管系统的结构改变。
