Jiménez-Puya Rafael, Vázquez-Bayo C, Rodriguez-Bujaldón A, Gómez García F, Moreno-Giménez José Carlos
Service of Dermatology, University Hospital Reina Sofía, Córdoba, Spain.
Pediatr Dermatol. 2009 Mar-Apr;26(2):213-4. doi: 10.1111/j.1525-1470.2008.00859.x. Epub 2009 Mar 18.
Severe combined immunodeficiency (SCID) is a heterogeneous group of disorders characterized by a defect of T and B cell immunity with a genetic origin in most cases. Although the X-linked recessive form is most common (60-70%), there are autosomal recessive forms (20%) and spontaneous mutations. While SCID may present with many nosocomial infections, dermatophyte infections are not common. We reported a case of SCID which was associated with a widespread skin infection with Trichophyton mentagrophytes.
重症联合免疫缺陷（SCID）是一组异质性疾病，其特征是T和B细胞免疫缺陷，大多数情况下为遗传起源。虽然X连锁隐性形式最为常见（60 - 70%），但也有常染色体隐性形式（20%）和自发突变。虽然SCID可能会出现许多医院感染，但皮肤癣菌感染并不常见。我们报告了一例与广泛的须癣毛癣菌皮肤感染相关的SCID病例。
