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运动干预降低低骨密度个体与跌倒相关的骨折及其风险因素:一项随机对照试验的系统评价。

Exercise interventions to reduce fall-related fractures and their risk factors in individuals with low bone density: a systematic review of randomized controlled trials.

机构信息

Department of Rehabilitation, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

出版信息

Osteoporos Int. 2009 Dec;20(12):2111-25. doi: 10.1007/s00198-009-0938-6. Epub 2009 May 7.

Abstract

SUMMARY

Exercise can reduce falls and fall-related fractures in healthy individuals; however, evidence for individuals with low BMD is limited. The results from this systematic review indicate that exercise interventions for individuals with low BMD to reduce falls and fractures should include balance, muscle strengthening, and weight-bearing exercises.

INTRODUCTION

The purpose of this systematic review was to investigate which exercise interventions are effective in individuals with low bone mineral density (BMD; osteopenia or osteoporosis) in reducing (1) falls and fractures and (2) risk factors for falls and fractures.

METHODS

Databases were searched for relevant studies between 1996 and June 2008. Methodological quality was assessed with the Jadad score and the PEDro scale.

RESULTS

Of the 1,369 publications found, 23 met the inclusion criteria. Five additional articles were included after checking reference lists and searching author's names and related articles. Interventions with balance exercises reduced falls or fall-related fractures and improved balance in the majority of the studies. Muscle strengthening exercises were effective in improving lower extremity strength and back extensor strength; however, not all RCT's reported positive effects. Bone strength was improved by weight-bearing aerobic exercise with or without muscle strengthening exercise when the duration of the intervention was at least a year.

CONCLUSIONS

Exercise can reduce falls, fall-related fractures, and several risk factors for falls in individuals with low BMD. Exercise interventions for patients with osteoporosis should include weight-bearing activities, balance exercise, and strengthening exercises to reduce fall and fracture risk.

摘要

摘要

运动可以降低健康个体的跌倒发生率和与跌倒相关的骨折发生率;然而,针对低骨密度个体的证据有限。本系统评价的结果表明,针对低骨密度个体的运动干预措施,应包括平衡、肌肉强化和负重锻炼,以降低跌倒和骨折的风险。

引言

本系统评价的目的是调查哪些运动干预措施对低骨密度(骨质减少或骨质疏松症)个体有效,可降低(1)跌倒和骨折的发生率,以及(2)跌倒和骨折的风险因素。

方法

从 1996 年至 2008 年 6 月期间,对数据库进行了相关研究的检索。采用 Jadad 评分和 PEDro 量表评估方法学质量。

结果

在检索到的 1369 篇文献中,有 23 篇符合纳入标准。在查阅参考文献和检索作者姓名及相关文章后,又纳入了另外 5 篇文章。在大多数研究中,平衡运动干预措施可降低跌倒或与跌倒相关的骨折发生率,并改善平衡能力。肌肉强化运动可有效增强下肢力量和腰背伸肌力量;然而,并非所有 RCT 都报告了积极的效果。负重有氧运动结合或不结合肌肉强化运动,如果干预时间至少为一年,可改善骨强度。

结论

运动可以降低低骨密度个体的跌倒发生率、与跌倒相关的骨折发生率和跌倒的几个风险因素。针对骨质疏松症患者的运动干预措施应包括负重活动、平衡运动和强化锻炼,以降低跌倒和骨折的风险。

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