Uçar Ülkü, Çubukçu Fırat Sibel, Ozdemir Tülay, Lüleci Ersin
Department of Rheumatology, Antalya Research and Training Hospital, Antalya, Türkiye.
Department of Physical Medicine and Rehabilitation, Akdeniz University Medical Faculty, Antalya, Türkiye.
Arch Rheumatol. 2025 Jun 23;40(2):211-220. doi: 10.5152/ArchRheumatol.2025.11032.
Background/Aims: The aim was to investigate the effectiveness of exercise on muscle strength, lung capacity, spinal mobility, endurance, and quality of life (QoL) in postmenopausal osteoporosis patients without vertebral fractures. Materials and Methods: This study was conducted with 41 postmenopausal osteoporosis patients (aged 45-65 years) without osteoporotic fractures. Patients were randomized into 2 groups. The patients in the exercise group (EG) were given an exercise regimen (breathing, stretching, relaxation, balance, and strengthening exercises) 3 times a week for 8 weeks at the department. Patients in the control group were kept on their current medical treatment. A Cybex Isokinetic Dynamometer and a Saunders digital inclinometer were used to assess back extensor muscle strength and spinal mobility. Pulmonary function tests were performed with a Jaeger spirometer. "Timed loaded standing" method, Quality of Life Questionnaire of the European Foundation for Osteoporosis 41 (QUALEFFO-41) and Short Form Health Survey 36 (SF-36) were used to evaluate the impact of exercise on back endurance and QoL respectively. Results: Baseline demographic and clinical characteristics were similar between the 2 groups. At the end of the study, statistically significant improvements were noted in the EG's back extensor strength and endurance compared to baseline values (P < .05). Vital capacity, forced vital capacity, forced expiratory volume during the first second, maximal mid-expiratory flow rate, maximum inspiratory pressure measurements, and scores for QoL (physical function, mental function sub-scores, and total QUALEFFO-41 score, physical function, and vitality sub-scores of SF-36) were also significantly improved in the EG (P < .05). Spinal mobility of patients remained unchanged at the end of the study for both groups (P > .05). Conclusion: Muscle strength, trunk endurance, pulmonary functions, and QoL are known to be affected in postmenopausal osteoporosis patients. The findings supported that significant improvements can be achieved in these parameters even with appropriate short-term exercise in fracturefree periods.
背景/目的：本研究旨在调查运动对无椎体骨折的绝经后骨质疏松症患者肌肉力量、肺容量、脊柱活动度、耐力和生活质量（QoL）的有效性。材料与方法：本研究纳入41例年龄在45 - 65岁之间、无骨质疏松性骨折的绝经后骨质疏松症患者。患者被随机分为两组。运动组（EG）患者在科室接受为期8周、每周3次的运动方案（呼吸、伸展、放松、平衡和强化运动）。对照组患者维持当前治疗。使用Cybex等速测力计和桑德斯数字倾角仪评估背部伸肌力量和脊柱活动度。用耶格肺功能仪进行肺功能测试。分别采用“定时负重站立”法、欧洲骨质疏松症基金会生活质量问卷41项（QUALEFFO - 41）和简短健康调查问卷36项（SF - 36）评估运动对背部耐力和生活质量的影响。结果：两组的基线人口统计学和临床特征相似。研究结束时，与基线值相比，运动组的背部伸肌力量和耐力有统计学意义的显著改善（P < 0.05）。运动组的肺活量、用力肺活量、第1秒用力呼气量、最大呼气中期流速、最大吸气压力测量值以及生活质量评分（身体功能、心理功能子评分、QUALEFFO - 41总分、SF - 36的身体功能和活力子评分）也有显著改善（P < 0.05）。两组患者在研究结束时脊柱活动度均未改变（P > 0.05）。结论：已知绝经后骨质疏松症患者的肌肉力量、躯干耐力、肺功能和生活质量会受到影响。研究结果支持，即使在无骨折期进行适当的短期运动，这些参数也能得到显著改善。
